Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 2/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11942673 | 0.92 | TRPV1 (0.43) | P2RY14CYP17A1PSMB8MAPTIDH1 | |
| SCHEMBL1261441 | 0.91 | ABCG2 (0.43) | ABCG2CYP3A4MAPTATMNPSR1 | |
| SCHEMBL11942679 | 0.90 | ABCG2 (0.36) | P2RY14ABCG2MTORCYP3A4MAPT | |
| SCHEMBL11942665 | 0.87 | NPC1 (0.43) | ABCG2CYP3A4MAPTATMNPSR1 | |
| SCHEMBL2743411 | 0.87 | MAPT (0.40) | ABCG2CYP3A4MAPTATMNPSR1 | |
| SCHEMBL11942664 | 0.86 | CHRNA7 (0.43) | MAPTABL1TRPV1 | |
| SCHEMBL2743576 | 0.86 | ABCG2 (0.39) | ABCG2CYP3A4MAPTATMNPSR1 | |
| SCHEMBL16078277 | 0.85 | KCNQ3 (0.45) | ABCG2CYP3A4MAPTATMNPSR1 | |
| SCHEMBL16073030 | 0.84 | CYP17A1 (0.46) | P2RY14CYP17A1MTORPSMB8MAP4K4 | |
| SCHEMBL11952866 | 0.83 | MAPT (0.41) | MAPTABL1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376401-B2 | Preparation of 1,3-(substituted-diaryl)-1,2,4-triazoles and intermediates therefrom | DOW AGROSCIENCES LLC (US) | 2016-06-28 | — | — | US | disclosed |
| US-9376401-B2 | Preparation of 1,3-(substituted-diaryl)-1,2,4-triazoles and intermediates therefrom | DOW AGROSCIENCES LLC (US) | 2016-06-28 | — | — | US | disclosed |
| EP-2461688-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| EP-2461688-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| US-8927729-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-8927729-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-8927729-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2015-01-06 | — | — | US | disclosed |
| WO-2014163934-A1 | PREPARATION OF 1,3-(SUBSTITUTED-DIARYL)-1,2,4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2014-10-09 | — | — | WO | disclosed |
| WO-2014158648-A1 | PREPARATION OF 1,3-(SUBSTITUTED-DIARYL)-1,2,4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014158649-A1 | PREPARATION OF 1,3-(SUBSTITUTED-DIARYL)-1,2,4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20140275556-A1 | PREPARATION OF 1,3-(SUBSTITUTED-DIARYL)-1,2,4-TRIAZOLES AND INTERMEDIATES THEREFROM | DOW AGROSCIENCES LLC (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140135364-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-05-15 | — | — | US | disclosed |
| US-20140135364-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-05-15 | — | — | US | disclosed |
| US-8674109-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2014-03-18 | — | — | US | disclosed |
| US-8674109-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2014-03-18 | — | — | US | disclosed |
| US-8674109-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2014-03-18 | — | — | US | disclosed |
| US-20120190543-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190543-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190543-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| WO-2011017513-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190543-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, AADAC | P2RY14 1347/4885CYP17A1 2032/4885ABCG2 1643/4885 |
| US-20140275556-A1 | PREPARATION OF 1,3-(SUBSTITUTED-DIARYL)-1,2,4-TRIAZOLES AND INTERMEDIATES THEREFROM | DDT, CYP51A1, WEE1 | P2RY14 2323/4885CYP17A1 428/4885ABCG2 3109/4885 |
| US-20140135364-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PLCG2 | P2RY14 426/4885CYP17A1 1271/4885ABCG2 1102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.