Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATF4 | P18848 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260593 | 0.91 | EPHX2 (0.46) | ABL1MAPTLMNAEPHX2SMN1; SMN2 | |
| SCHEMBL2743411 | 0.90 | MAPT (0.40) | ABCG2ATMNPSR1ABL1MAPT | |
| SCHEMBL1261441 | 0.88 | ABCG2 (0.43) | ABCG2ATMNPSR1ABL1MAPT | |
| SCHEMBL2743577 | 0.86 | MAPT (0.36) | ABCG2ATMNPSR1ABL1MAPT | |
| SCHEMBL11029675 | 0.86 | P2RY14 (0.42) | ABCG2ATMNPSR1ABL1MAPT | |
| SCHEMBL16078277 | 0.85 | KCNQ3 (0.45) | ABCG2ATMNPSR1MAPTCYP3A4 | |
| SCHEMBL11942665 | 0.85 | NPC1 (0.43) | ABCG2ATMNPSR1ABL1MAPT | |
| SCHEMBL17454037 | 0.83 | PGR (0.47) | ABCG2MAPTCYP3A4LMNATP53 | |
| SCHEMBL28429104 | 0.83 | CHRNA7 (0.37) | ABCG2CYP3A4CHRNA7 | |
| SCHEMBL1260336 | 0.83 | ALDH1A1 (0.39) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732109-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2017-08-15 | — | — | US | disclosed |
| EP-2247603-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-09-28 | — | — | EP | disclosed |
| US-9018363-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-04-28 | — | — | US | disclosed |
| US-9006468-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-20150080326-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-03-19 | — | — | US | disclosed |
| US-20120172218-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120122805-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-05-17 | — | — | US | disclosed |
| US-8178658-B2 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| EP-2247603-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009102736-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2009-08-20 | — | — | WO | disclosed |
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES LLC (US) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DDT, ACHE, NANP | ABCG2 619/4885ATM 4093/4885NPSR1 521/4885 |
| US-20120172218-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | ABCG2 3109/4885ATM 4614/4885NPSR1 2074/4885 |
| US-20150080326-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | ABCG2 3109/4885ATM 4614/4885NPSR1 2074/4885 |
| US-20120122805-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | ABCG2 3109/4885ATM 4614/4885NPSR1 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.