Ethylene Glycol

Ethylene Glycol

SCHEMBL11029757

O=C1OCCCCCCOC(=O)c2cccc1c2.OCCO

nearest known ligand 0.33

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.33
NAAA Q02083 2/20 0.33
PGR P06401 2/20 0.33
KMO O15229 1/20 0.32
CCNC P24863 1/20 0.32
CDK8 P49336 1/20 0.32
IDH2 P48735 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30
CA1 P00915 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL2282874 1.00 FAAH (0.33) FAAHNAAAPGRKMOCCNC
Ethylene Glycol SCHEMBL27650882 0.90 KDM4E (0.36) FAAHNAAAKDM4EALDH1A1LMNA
SCHEMBL4746687 0.90 CA1 (0.36) FAAHNAAAPGRKMOCCNC
SCHEMBL9436552 0.90 CA1 (0.36) FAAHNAAAPGRKMOCCNC
SCHEMBL4749824 0.90 CA1 (0.36) FAAHNAAAPGRKMOCCNC
SCHEMBL10867639 0.90 CA1 (0.36) FAAHNAAAPGRKMOCCNC
SCHEMBL29684239 0.88 IDH2 (0.35) FAAHNAAAPGRKMOCCNC
SCHEMBL209608 0.88 CA1 (0.37) FAAHNAAAKMOKDM4EALDH1A1
Ethylene Glycol SCHEMBL2285797 0.86 CA1 (0.33) FAAHNAAAPGRCA1CA9
Ethylene SCHEMBL28503705 0.86 CA1 (0.33) FAAHNAAAPGRKMOCCNC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0043073-B1 PHOTOCURABLE POLYURETHANE FILM COATINGS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-10-16 EP claimed
US-4337130-A COMPRISING AN ALIPHATIC DIISOCYANATE, POLY (HEXAMETHYLENE ISOPHTHALATE) GLYCOL, ACRYLIC ESTER, PHOTOINITIATOR AND ANTI-OXIDANT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-06-29 US claimed
EP-0043073-A2 Photocurable polyurethane film coatings E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-01-06 EP claimed
EP-0043073-B1 PHOTOCURABLE POLYURETHANE FILM COATINGS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-10-16 EP disclosed
US-4337130-A COMPRISING AN ALIPHATIC DIISOCYANATE, POLY (HEXAMETHYLENE ISOPHTHALATE) GLYCOL, ACRYLIC ESTER, PHOTOINITIATOR AND ANTI-OXIDANT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-06-29 US disclosed
EP-0043073-A2 Photocurable polyurethane film coatings E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-01-06 EP disclosed
US-4097439-A Polyurethane coating composition curable by addition polymerization E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-06-27 US disclosed