SCHEMBL4746687

SCHEMBL4746687

O=C1OCCCCCCCCCCCCCCCCCCCCOC(=O)c2cccc1c2

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.36
CA9 Q16790 1/20 0.36
PGR P06401 2/20 0.33
KMO O15229 1/20 0.33
NAMPT P43490 1/20 0.33
IDH2 P48735 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
FAAH O00519 1/20 0.33
NAAA Q02083 1/20 0.33
CLK1 P49759 1/20 0.33
DYRK1A Q13627 1/20 0.33
DYRK1B Q9Y463 1/20 0.33
CCNC P24863 1/20 0.32
CDK8 P49336 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10867639 1.00 CA1 (0.36) CA1CA9PGRKMONAMPT
SCHEMBL4749824 1.00 CA1 (0.36) CA1CA9PGRKMONAMPT
SCHEMBL9436552 1.00 CA1 (0.36) CA1CA9PGRKMONAMPT
SCHEMBL29684239 0.98 IDH2 (0.35) CA1CA9PGRKMONAMPT
SCHEMBL209608 0.98 CA1 (0.37) CA1CA9KMONAMPTMAPT
Ethylene SCHEMBL28503705 0.96 CA1 (0.33) CA1CA9PGRKMONAMPT
SCHEMBL10875555 0.93 CA9 (0.34) CA1CA9KMONAMPTMAPT
SCHEMBL212973 0.93 KMT2A (0.34) CA1CA9NAMPTMAPTKMT2A
SCHEMBL29833169 0.91 FAAH (0.33) CA1CA9NAMPTIDH2MAPT
Ethylene Glycol SCHEMBL11029757 0.90 FAAH (0.33) CA1CA9PGRKMOIDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10695462-B2 On-demand degradable medical devices YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2020-06-30 US claimed
US-20170312388-A1 ON-DEMAND DEGRADABLE MEDICAL DEVICES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2017-11-02 US claimed
EP-3204060-A1 ON-DEMAND DEGRADABLE MEDICAL DEVICES Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2017-08-16 EP claimed
WO-2016056008-A1 ON-DEMAND DEGRADABLE MEDICAL DEVICES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2016-04-14 WO claimed
WO-2002090245-A2 METHODS OF FORMING MICROSTRUCTURE DEVICES APPLIED MATERIALS, INC. (US) 2002-11-14 WO claimed
EP-3361967-B1 INSTRUMENT HANDLE AND REPLACEABLE TIP KATALYST SURGICAL LLC (US) 2025-09-03 EP disclosed
US-11160935-B2 Reusable instrument handle with single-use tip KATALYST SURGICAL, LLC (US) 2021-11-02 US disclosed
US-10772676-B2 Microsurgical bipolar forceps Kogent Surgical, LLC (US) 2020-09-15 US disclosed
US-10709504-B2 Curved laser probe with single-use optic fiber KATALYST SURGICAL, LLC (US) 2020-07-14 US disclosed
US-10695462-B2 On-demand degradable medical devices YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2020-06-30 US disclosed
US-10646113-B2 Illuminated cannula KATALYST SURGICAL, LLC (US) 2020-05-12 US disclosed
EP-3373873-B1 LASER PROBE WITH REPLACEABLE OPTIC FIBERS KATALYST SURGICAL LLC (US) 2020-02-19 EP disclosed
US-20170135859-A1 LASER PROBE WITH REPLACEABLE OPTIC FIBERS KATALYST SURGICAL, LLC (US) 2017-05-18 US disclosed
WO-2017083097-A1 LASER PROBE WITH REPLACEABLE OPTIC FIBERS KATALYST SURGICAL, LLC (US) 2017-05-18 WO disclosed
WO-2017066026-A1 INSTRUMENT HANDLE AND REPLACEABLE TIP KATALYST SURGICAL, LLC (US) 2017-04-20 WO disclosed
US-20170100114-A1 INSTRUMENT HANDLE AND REPLACEABLE TIP KATALYST SURGICAL, LLC (US) 2017-04-13 US disclosed
WO-2016056008-A1 ON-DEMAND DEGRADABLE MEDICAL DEVICES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2016-04-14 WO disclosed
WO-2008122763-A1 METHOD OF PEST AND FUNGAL CONTROL SYNGENTA PARTICIPATIONS AG (CH) 2008-10-16 WO disclosed
WO-2008123955-A1 ARTICLES WITH SUPER-HYDROPHOBIC AND-OR SUPER HYDROPHILIC SURFACES AND METHOD OF FORMATION APPLIED MICROSTRUCTURES, INC. (US) 2008-10-16 WO disclosed
WO-2007042185-A2 GRANULAR COMPOSITIONS AND METHODS FOR COMBATTING RICE PESTS AND FUNGAL DISEASES SYNGENTA PARTICIPATIONS AG (CH) 2007-04-19 WO disclosed