SCHEMBL11030265

SCHEMBL11030265

O=C(F)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.60
MAPT P10636 4/20 0.60
RAB9A P51151 3/20 0.56
NPC1 O15118 1/20 0.56
CTDSP1 Q9GZU7 1/20 0.56
L3MBTL1 Q9Y468 2/20 0.54
PTPN1 P18031 2/20 0.54
GSK3B P49841 1/20 0.54
LMNA P02545 2/20 0.52
CDC25B P30305 1/20 0.52
ATM Q13315 1/20 0.52
FFAR1 O14842 1/20 0.52
CYP1A2 P05177 1/20 0.52
HIF1A Q16665 1/20 0.52
HPGD P15428 3/20 0.50
ERCC5 P28715 1/20 0.50
FEN1 P39748 1/20 0.50
HAO1 Q9UJM8 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12212918 0.89 BCL2L1 (0.50) SMN1; SMN2MAPTRAB9ANPC1CTDSP1
SCHEMBL9315856 0.88 HPGD (0.53) SMN1; SMN2MAPTRAB9ANPC1CTDSP1
SCHEMBL11425374 0.88 PARP10 (0.53) SMN1; SMN2MAPTRAB9ANPC1CTDSP1
SCHEMBL295618 0.84
SCHEMBL7378830 0.84 CES1 (0.58) SMN1; SMN2MAPTL3MBTL1GSK3BLMNA
Hydrochloric Acid SCHEMBL27691884 0.81 CES1 (0.55) SMN1; SMN2MAPTL3MBTL1GSK3BLMNA
Fluoride SCHEMBL21291892 0.81 CES1 (0.55) SMN1; SMN2MAPTL3MBTL1GSK3BLMNA
Hydrochloric Acid SCHEMBL27436699 0.81 CES1 (0.55) SMN1; SMN2MAPTL3MBTL1GSK3BLMNA
Fluoride SCHEMBL27434180 0.81 CES1 (0.55) SMN1; SMN2MAPTL3MBTL1GSK3BLMNA
Biphenyl SCHEMBL29282083 0.81 ALDH1A1 (0.60) SMN1; SMN2MAPTRAB9ANPC1CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115717009-B Perovskite ink and preparation method and application thereof 江苏集萃有机光电技术研究所有限公司 2023-11-14 CN claimed
CN-115717009-A Perovskite ink and preparation method and application thereof 江苏集萃有机光电技术研究所有限公司 2023-02-28 CN claimed
CN-103180308-B Process for preparing benzimidazole derivatives DAE WOONG PHARMA 2015-04-08 CN claimed
CN-119191926-A Synthesis method of gamma-amino ketone 兰州大学 2024-12-27 CN disclosed
CN-115717009-B Perovskite ink and preparation method and application thereof 江苏集萃有机光电技术研究所有限公司 2023-11-14 CN disclosed
CN-115717009-A Perovskite ink and preparation method and application thereof 江苏集萃有机光电技术研究所有限公司 2023-02-28 CN disclosed
CN-114773185-B Method for synthesizing benzoyl fluoride compound by utilizing sodium trifluoromethanesulphinate 南京理工大学 2023-01-03 CN disclosed
CN-114773185-A Method for synthesizing benzoyl fluoride compound by using sodium trifluoromethanesulphinate 南京理工大学 2022-07-22 CN disclosed
CN-103180308-B Process for preparing benzimidazole derivatives DAE WOONG PHARMA 2015-04-08 CN disclosed
CN-101413143-B Compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding SCRIPPS RESEARCH INST 2013-09-18 CN disclosed
CN-101413143-A Compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding SCRIPPS RESEARCH INST (US) 2009-04-22 CN disclosed
CN-100448852-C Compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding SCRIPPS RESEARCH INST (US) 2009-01-07 CN disclosed
CN-1747965-A Compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding SCRIPPS RESEARCH INST (US) 2006-03-15 CN disclosed
US-4555370-A CYANTATION OF ACYL. FLUORIDE BAYER AKTIENGESELLSCHAFT (DE) 1985-11-26 US disclosed