Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GALK1 | P51570 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11030351 | 1.00 | KDM4E (0.35) | KDM4EALDH1A1HSD17B10KMOMEP1B | |
| SCHEMBL11028098 | 0.90 | KDM4E (0.36) | KDM4EALDH1A1HSD17B10KMOMEP1B | |
| SCHEMBL11028097 | 0.90 | KDM4E (0.36) | KDM4EALDH1A1HSD17B10KMOMEP1B | |
| SCHEMBL11030755 | 0.84 | KDM4E (0.35) | KDM4EALDH1A1HSD17B10KMOMEP1B | |
| SCHEMBL11030759 | 0.84 | KDM4E (0.35) | KDM4EALDH1A1HSD17B10KMOMEP1B | |
| SCHEMBL14353876 | 0.84 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10KMOMEP1B | |
| SCHEMBL29370743 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10KMOMEP1B | |
| SCHEMBL29390242 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10KMOMEP1B | |
| SCHEMBL2471056 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10KMOMEP1B | |
| SCHEMBL20611096 | 0.82 | KDM4E (0.40) | KDM4EALDH1A1HSD17B10KMOMEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2899182-B1 | Arylalkyl esters of 4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2018-01-10 | — | — | EP | disclosed |
| US-9169217-B2 | Arylalkyl esters of 4-amino-6-(substituted phenyl)-picolinates and 6-amino-2-(substituted phenyl)-pyrimidinecarboxylates and their use as selective herbicides for crops | DOW AGROSCIENCES LLC (US) | 2015-10-27 | — | — | US | disclosed |
| EP-2899182-A1 | Arylalkyl esters of 4-aminopicolinates and their use as herbicides | Dow AgroSciences LLC (US) | 2015-07-29 | — | — | EP | disclosed |
| US-20150025238-A1 | ARYLALKYL ESTERS OF 4-AMINO-6-(SUBSTITUTED PHENYL)-PICOLINATES AND 6-AMINO-2-(SUBSTITUTED PHENYL)-PYRIMIDINECARBOXYLATES AND THEIR USE AS SELECTIVE HERBICIDES FOR CROPS | DOW AGROSCIENCES LLC (US) | 2015-01-22 | — | — | US | disclosed |
| US-8883688-B2 | Arylalkyl esters of 4-amino-6-(substituted phenyl)-picolinates and 6-amino-2-(substituted phenyl)-pyrimidinecarboxylates and their use as selective herbicides for crops | DOW AGROSCIENCES, LLC. (US) | 2014-11-11 | — | — | US | disclosed |
| EP-2667716-A1 | ARYLALKYL ESTERS OF 4-AMINO-6-(SUBSTITUTED PHENYL)PICOLINATES AND 6-AMINO-2-(SUBSTITUTED PHENYL)-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2013-12-04 | — | — | EP | disclosed |
| WO-2012103042-A1 | ARYLALKYL ESTERS OF 4-AMINO-6-(SUBSTITUTED PHENYL)PICOLINATES AND 6-AMINO-2-(SUBSTITUTED PHENYL)-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2012-08-02 | — | — | WO | disclosed |
| US-20120190551-A1 | ARYLALKYL ESTERS OF 4-AMINO-6-(SUBSTITUTED PHENYL)-PICOLINATES AND 6-AMINO-2-(SUBSTITUTED PHENYL)-PYRIMIDINECARBOXYLATES AND THEIR USE AS SELECTIVE HERBICIDES FOR CROPS | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190551-A1 | ARYLALKYL ESTERS OF 4-AMINO-6-(SUBSTITUTED PHENYL)-PICOLINATES AND 6-AMINO-2-(SUBSTITUTED PHENYL)-PYRIMIDINECARBOXYLATES AND THEIR USE AS SELECTIVE HERBICIDES FOR CROPS | PLPBP, AADAC, HPD | KDM4E 203/4885ALDH1A1 1663/4885HSD17B10 2716/4885 |
| US-20150025238-A1 | ARYLALKYL ESTERS OF 4-AMINO-6-(SUBSTITUTED PHENYL)-PICOLINATES AND 6-AMINO-2-(SUBSTITUTED PHENYL)-PYRIMIDINECARBOXYLATES AND THEIR USE AS SELECTIVE HERBICIDES FOR CROPS | PLPBP, AADAC, HPD | KDM4E 203/4885ALDH1A1 1663/4885HSD17B10 2716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.