Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11031495 | 0.77 | MAPT (0.44) | ERBB2ALDH1A1HPGDMAPTLMNA | |
| SCHEMBL11027030 | 0.74 | ERBB2 (0.43) | ERBB2ALDH1A1HPGDMAPTLMNA | |
| SCHEMBL6165332 | 0.71 | KDM4E (0.35) | ALDH1A1HPGDMAPTLMNAL3MBTL1 | |
| SCHEMBL19244727 | 0.70 | KDM4E (0.43) | ALDH1A1HPGDMAPTLMNAL3MBTL1 | |
| SCHEMBL317654 | 0.70 | SMN1; SMN2 (0.46) | ALDH1A1HPGDMAPTLMNAL3MBTL1 | |
| SCHEMBL4678518 | 0.70 | ERBB2 (0.61) | ERBB2ALDH1A1HPGDLMNAL3MBTL1 | |
| SCHEMBL15440078 | 0.68 | CDH1 (0.42) | AHRCNR1KMO | |
| SCHEMBL603951 | 0.68 | MAPT (0.58) | ALDH1A1HPGDMAPTLMNAL3MBTL1 | |
| SCHEMBL15439892 | 0.68 | CDH1 (0.49) | L3MBTL1SMN1; SMN2CNR1KMO | |
| SCHEMBL4526244 | 0.67 | KDM4E (0.48) | MAPTLMNAL3MBTL1ADRB2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2667712-B1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2016-08-31 | — | — | EP | disclosed |
| EP-2667712-B1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2016-08-31 | — | — | EP | disclosed |
| US-8993772-B2 | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates | DOW AGROSCIENCES, LLC. (US) | 2015-03-31 | — | — | US | disclosed |
| US-8993772-B2 | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates | DOW AGROSCIENCES, LLC. (US) | 2015-03-31 | — | — | US | disclosed |
| US-8993772-B2 | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates | DOW AGROSCIENCES, LLC. (US) | 2015-03-31 | — | — | US | disclosed |
| US-20140206881-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-07-24 | — | — | US | disclosed |
| US-20140206881-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-07-24 | — | — | US | disclosed |
| US-20140206881-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-07-24 | — | — | US | disclosed |
| US-8754231-B2 | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates | DOW AGROSCIENCES, LLC. (US) | 2014-06-17 | — | — | US | disclosed |
| US-8754231-B2 | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates | DOW AGROSCIENCES, LLC. (US) | 2014-06-17 | — | — | US | disclosed |
| US-8754231-B2 | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates | DOW AGROSCIENCES, LLC. (US) | 2014-06-17 | — | — | US | disclosed |
| EP-2667712-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | Dow AgroSciences LLC (US) | 2013-12-04 | — | — | EP | disclosed |
| WO-2012103045-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2012-08-02 | — | — | WO | disclosed |
| US-20120190859-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190859-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190859-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190859-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | CYP4F3, CYP4F12, AFF4 | ERBB2 2022/4885AHR 558/4885ALDH1A1 2501/4885 |
| US-20140206881-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | CYP4F3, CYP4F12, AFF4 | ERBB2 2022/4885AHR 558/4885ALDH1A1 2501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.