Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDH1 | P12830 | 2/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.49 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | APC | P25054 | 1/20 | 0.49 |
| ▸ | KMO | O15229 | 3/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | RPA1 | P27694 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 4/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439882 | 0.88 | PIK3CA (0.48) | MCL1KMORPA1SMN1; SMN2CNR1 | |
| SCHEMBL15449707 | 0.87 | KMO (0.48) | KMORPA1SMN1; SMN2CNR1DHODH | |
| SCHEMBL15440078 | 0.87 | CDH1 (0.42) | CDH1CTNNB1TCF7L2APCKMO | |
| SCHEMBL15449353 | 0.84 | PRKAB2 (0.43) | MCL1KMOSMN1; SMN2CNR1GPR35 | |
| SCHEMBL15439943 | 0.83 | MCL1 (0.50) | MCL1RPA1SMN1; SMN2CNR1DHODH | |
| SCHEMBL15439889 | 0.78 | ALDH1A1 (0.45) | CNR1 | |
| SCHEMBL21044577 | 0.77 | MCL1 (0.69) | CDH1CTNNB1TCF7L2MCL1APC | |
| SCHEMBL15440485 | 0.77 | XDH (0.44) | SMN1; SMN2CNR1DHODHCTRCPTGER1 | |
| SCHEMBL10995427 | 0.76 | DHODH (0.49) | CDH1CTNNB1TCF7L2MCL1APC | |
| SCHEMBL2704945 | 0.75 | CNR1 (0.67) | CDH1CTNNB1TCF7L2APCKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026042-B | Method for fluorinating a compound | 美国陶氏益农公司 | 2022-01-04 | — | — | CN | disclosed |
| EP-2877452-B1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | DOW AGROSCIENCES LLC (US) | 2017-08-23 | — | — | EP | disclosed |
| EP-2877452-B1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | DOW AGROSCIENCES LLC (US) | 2017-08-23 | — | — | EP | disclosed |
| CN-104640844-B | The preparation method of 4-amino-5-fluorine-3-halo-6-(substituted) pyridine-2-formic acid esters | 美国陶氏益农公司 | 2016-11-09 | — | — | CN | disclosed |
| EP-2877453-B1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2016-07-06 | — | — | EP | disclosed |
| EP-2877453-B1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2016-07-06 | — | — | EP | disclosed |
| US-9376388-B2 | Fluoropicolinoyl fluorides and processes for their preparation | DOW AGROSCIENCES LLC (US) | 2016-06-28 | — | — | US | disclosed |
| US-9376388-B2 | Fluoropicolinoyl fluorides and processes for their preparation | DOW AGROSCIENCES LLC (US) | 2016-06-28 | — | — | US | disclosed |
| US-9376388-B2 | Fluoropicolinoyl fluorides and processes for their preparation | DOW AGROSCIENCES LLC (US) | 2016-06-28 | — | — | US | disclosed |
| US-20150191428-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | CORTEVA AGRISCIENCE LLC | 2015-07-09 | — | — | US | disclosed |
| US-8871943-B2 | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates | DOW AGROSCIENCES, LLC. (US) | 2014-10-28 | — | — | US | disclosed |
| US-8871943-B2 | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates | DOW AGROSCIENCES, LLC. (US) | 2014-10-28 | — | — | US | disclosed |
| US-20140031556-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | US | disclosed |
| US-20140031556-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | US | disclosed |
| US-20140031556-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | US | disclosed |
| WO-2014018502-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | WO | disclosed |
| WO-2014018506-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | WO | disclosed |
| US-20140031558-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | US | disclosed |
| US-20140031558-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | US | disclosed |
| US-20140031558-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031556-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | CLIC4, NPEPPS, CYP4F3 | CDH1 4776/4885CTNNB1 3033/4885TCF7L2 422/4885 |
| US-20150191428-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | FLI1, ABL1, FLNA | CDH1 3984/4885CTNNB1 1292/4885TCF7L2 105/4885 |
| US-20140031558-A1 | FLUOROPICOLINOYL FLUORIDES AND PROCESSES FOR THEIR PREPARATION | FLI1, ABL1, FLNA | CDH1 3984/4885CTNNB1 1292/4885TCF7L2 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.