SCHEMBL11030558

SCHEMBL11030558

Cc1cc(NCCCN)nc(Nc2ccccc2)c1C#N

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
KDM4E B2RXH2 6/20 0.47
HPGD P15428 5/20 0.46
GAA P10253 2/20 0.46
AURKA O14965 4/20 0.45
CYP3A4 P08684 3/20 0.45
CYP2D6 P10635 3/20 0.45
HSD17B10 Q99714 5/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
ABCB1 P08183 1/20 0.43
ABCG2 Q9UNQ0 1/20 0.43
STK17A Q9UEE5 1/20 0.43
TSHR P16473 1/20 0.42
RPS27 P42677 1/20 0.41
MAPK8 P45983 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10976698 0.94 ALDH1A1 (0.62) ALDH1A1KDM4EHPGDGAAAURKA
SCHEMBL11122384 0.91 ALDH1A1 (0.61) ALDH1A1KDM4EHPGDGAAAURKA
SCHEMBL9299773 0.89 ALDH1A1 (0.60) ALDH1A1KDM4EHPGDGAAAURKA
SCHEMBL9324539 0.87 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDGAAAURKA
SCHEMBL29785489 0.86 ALDH1A1 (0.61) ALDH1A1KDM4EHPGDGAAAURKA
SCHEMBL1497998 0.83 ALDH1A1 (0.76) ALDH1A1KDM4EHPGDGAAAURKA
SCHEMBL9324805 0.81 ALDH1A1 (0.55) ALDH1A1KDM4EHPGDGAAAURKA
SCHEMBL11133237 0.81 ALDH1A1 (0.54) ALDH1A1KDM4EHPGDGAAAURKA
SCHEMBL10102103 0.79 ALDH1A1 (0.68) ALDH1A1KDM4EHPGDGAAHSD17B10
SCHEMBL10985286 0.78 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDGAAAURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4500455-A RED DYE FOR CELLULOSE MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1985-02-19 US disclosed