Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | AURKA | O14965 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | MERTK | Q12866 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11122384 | 0.89 | ALDH1A1 (0.61) | ALDH1A1AURKAKDM4EHPGDGAA | |
| SCHEMBL11030558 | 0.89 | ALDH1A1 (0.61) | ALDH1A1AURKAKDM4EHPGDGAA | |
| SCHEMBL9324805 | 0.87 | ALDH1A1 (0.55) | ALDH1A1AURKAKDM4EHPGDGAA | |
| SCHEMBL9324539 | 0.86 | ALDH1A1 (0.57) | ALDH1A1AURKAKDM4EHPGDGAA | |
| SCHEMBL10976698 | 0.86 | ALDH1A1 (0.62) | ALDH1A1AURKAKDM4EHPGDGAA | |
| SCHEMBL10119067 | 0.85 | AURKA (0.64) | ALDH1A1AURKAKDM4EHPGDGAA | |
| SCHEMBL29785489 | 0.85 | ALDH1A1 (0.61) | ALDH1A1AURKAKDM4EHPGDGAA | |
| SCHEMBL10977375 | 0.82 | AURKA (0.55) | ALDH1A1AURKAKDM4EHPGDGAA | |
| SCHEMBL1497998 | 0.82 | ALDH1A1 (0.76) | ALDH1A1AURKAKDM4EHPGDGAA | |
| SCHEMBL11133237 | 0.80 | ALDH1A1 (0.54) | ALDH1A1AURKAKDM4EHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352774-A | Colorfast blue dyes for plastics and synthetic fibers | SANDOZ AG (CH) | 1994-10-04 | — | — | US | disclosed |
| US-5283326-A | Coupling azo and cyanine dyes; colorfastness, heat resistance | SANDOZ AG (CH) | 1994-02-01 | — | — | US | disclosed |
| EP-0201896-B1 | DYESTUFFS WITH THIOPHENE RESTS | BASF Aktiengesellschaft (DE) | 1990-05-02 | — | — | EP | disclosed |
| EP-0201896-A1 | Dyestuffs with thiophene rests | BASF Aktiengesellschaft (DE) | 1986-11-20 | — | — | EP | disclosed |