SCHEMBL11030600

SCHEMBL11030600

O=C(O)c1cc(S(=O)(=O)Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DTYMK P23919 1/20 0.57
CASP6 P55212 1/20 0.46
SLC25A1 P53007 1/20 0.45
POLB P06746 2/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
MMP1 P03956 1/20 0.43
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
MMP8 P22894 1/20 0.43
MMP13 P45452 1/20 0.43
TSHR P16473 2/20 0.42
LMNA P02545 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
TTR P02766 1/20 0.42
PPOX P50336 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
FLT1 P17948 1/20 0.40
FLT4 P35916 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7322857 0.85 DTYMK (0.58) DTYMKCASP6SLC25A1POLBCA1
SCHEMBL28969126 0.83 DTYMK (0.57) DTYMKCASP6SLC25A1POLBCA1
SCHEMBL1625062 0.83 DTYMK (0.57) DTYMKCASP6SLC25A1POLBCA1
SCHEMBL1625063 0.82 DTYMK (0.55) DTYMKCASP6SLC25A1POLBCA1
SCHEMBL4826675 0.82 DTYMK (0.55) DTYMKCASP6SLC25A1POLBCA1
SCHEMBL9499198 0.81 DTYMK (0.54) DTYMKCASP6SLC25A1POLBTSHR
SCHEMBL6564232 0.81 DTYMK (0.54) DTYMKCASP6SLC25A1POLBTSHR
SCHEMBL28444471 0.81 CA1 (0.44) DTYMKCASP6SLC25A1POLBCA1
SCHEMBL9658492 0.78 DTYMK (0.51) DTYMKCASP6SLC25A1POLBCA2
SCHEMBL9658489 0.78 DTYMK (0.51) DTYMKCASP6SLC25A1POLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4505913-A Substituted anthranilamides and pharmaceutical preparations containing these compounds CIBA-GEIGY CORPORATION (US) 1985-03-19 US disclosed