Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10921024 | 0.80 | GPR35 (0.50) | ALDH1A1TSHRCASP6VCAM1POLB | |
| SCHEMBL7322857 | 0.80 | DTYMK (0.58) | DTYMKALDH1A1TSHRCASP6POLB | |
| SCHEMBL9499198 | 0.79 | DTYMK (0.54) | DTYMKTSHRCASP6POLBSLC25A1 | |
| SCHEMBL11030600 | 0.78 | DTYMK (0.57) | DTYMKALDH1A1TSHRCASP6POLB | |
| SCHEMBL1625062 | 0.78 | DTYMK (0.57) | DTYMKALDH1A1TSHRCASP6POLB | |
| SCHEMBL28969126 | 0.78 | DTYMK (0.57) | DTYMKALDH1A1TSHRCASP6POLB | |
| SCHEMBL4826675 | 0.77 | DTYMK (0.55) | DTYMKALDH1A1TSHRCASP6POLB | |
| SCHEMBL1625063 | 0.77 | DTYMK (0.55) | DTYMKALDH1A1TSHRCASP6POLB | |
| SCHEMBL9501001 | 0.77 | KDM4E (0.49) | ALDH1A1CASP6POLBLMNAMEN1 | |
| SCHEMBL10924983 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TSHRVCAM1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5101069-A | PROCESS FOR THE PREPARATION OF HYDROXYETHYLSULFONYLNITRO- AND HYDROXYETHYLSULFONYLAMINO-BENZOIC ACIDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |
| US-4960929-A | Chemical intermediate for making fiber reactive azo dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |