SCHEMBL11031270

SCHEMBL11031270

CCOC(=O)Oc1c(Br)cc(C#N)cc1[N+](=O)[O-]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 3/20 0.41
ALDH1A1 P00352 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
KDM4E B2RXH2 2/20 0.38
POLB P06746 3/20 0.38
GALR2 O43603 1/20 0.38
MITF O75030 1/20 0.38
LMNA P02545 1/20 0.38
HSP90AA1 P07900 1/20 0.38
HPGD P15428 1/20 0.38
XBP1 P17861 1/20 0.38
CCR6 P51684 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MAPT P10636 3/20 0.37
KMT2A Q03164 1/20 0.36
GPR35 Q9HC97 1/20 0.36
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35
GRIN1 Q05586 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11175374 0.87 VCAM1 (0.39) VCAM1ALDH1A1TDP1LMNASMN1; SMN2
SCHEMBL11030903 0.87 VCAM1 (0.39) VCAM1ALDH1A1TDP1POLBLMNA
SCHEMBL11027338 0.86 VCAM1 (0.44) VCAM1ALDH1A1TDP1POLBMAPT
SCHEMBL11033590 0.85 VCAM1 (0.41) VCAM1ALDH1A1TDP1KDM4EPOLB
SCHEMBL11028679 0.85 VCAM1 (0.39) VCAM1ALDH1A1TDP1KDM4EMAPT
SCHEMBL11032697 0.83 TDP1 (0.49) VCAM1TDP1MAPTKMT2AGPR35
SCHEMBL11028674 0.80 VCAM1 (0.40) VCAM1ALDH1A1LMNAHPGDCCR6
SCHEMBL1734088 0.77 VCAM1 (0.51) VCAM1POLBMAPTKMT2AGPR35
SCHEMBL11033029 0.77 VCAM1 (0.42) VCAM1HPGDCCR6NPSR1MAPT
SCHEMBL11035522 0.74 VCAM1 (0.45) VCAM1ALDH1A1HPGDCCR6NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4486222-A POSTEMERGENCE CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1984-12-04 US disclosed
EP-0092632-A1 New benzonitrile derivatives, method for their preparation and herbicidal compositions CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1983-11-02 EP disclosed