Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10564088 | 1.00 | LMNA (0.37) | LMNAKMT2AMEN1MAPTHTT | |
| SCHEMBL9862119 | 1.00 | LMNA (0.37) | LMNAKMT2AMEN1MAPTHTT | |
| SCHEMBL9324059 | 0.88 | LMNA (0.36) | LMNAKMT2AMEN1MAPTHTT | |
| SCHEMBL11035168 | 0.88 | LMNA (0.36) | LMNAKMT2AMEN1MAPTHTT | |
| SCHEMBL9324444 | 0.88 | LMNA (0.36) | LMNAKMT2AMEN1MAPTHTT | |
| SCHEMBL9324344 | 0.88 | LMNA (0.36) | LMNAKMT2AMEN1MAPTHTT | |
| Hydrochloric Acid SCHEMBL9862121 | 0.86 | LMNA (0.35) | LMNAKMT2AMEN1MAPTHTT | |
| SCHEMBL18211316 | 0.84 | LMNA (0.39) | LMNAKMT2AMEN1MAPTHTT | |
| SCHEMBL9862124 | 0.81 | LMNA (0.38) | LMNAKMT2AMEN1MAPTHTT | |
| SCHEMBL7102385 | 0.78 | HPGD (0.47) | LMNAKMT2AMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4489093-A | Insecticidal esters | ROUSSEL UCLAF (FR) | 1984-12-18 | — | — | US | disclosed |