Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862140 | 0.84 | LMNA (0.44) | LMNAKMT2ATDP1MEN1TSHR | |
| SCHEMBL294885 | 0.84 | LMNA (0.44) | LMNAKMT2ATDP1MEN1TSHR | |
| SCHEMBL10828060 | 0.84 | LMNA (0.44) | LMNAKMT2ATDP1MEN1TSHR | |
| SCHEMBL293500 | 0.84 | LMNA (0.42) | LMNAKMT2ATDP1MEN1TSHR | |
| SCHEMBL293501 | 0.84 | LMNA (0.42) | LMNAKMT2ATDP1MEN1TSHR | |
| SCHEMBL9862119 | 0.81 | LMNA (0.37) | LMNAKMT2ATDP1MEN1TSHR | |
| SCHEMBL11031341 | 0.81 | LMNA (0.37) | LMNAKMT2ATDP1MEN1TSHR | |
| SCHEMBL10564088 | 0.81 | LMNA (0.37) | LMNAKMT2ATDP1MEN1TSHR | |
| SCHEMBL11035168 | 0.80 | LMNA (0.36) | LMNAKMT2ATDP1MEN1TSHR | |
| SCHEMBL9324344 | 0.80 | LMNA (0.36) | LMNAKMT2ATDP1MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004822-A | Isomers of 3-acetyl-2,2-dimethyl cyclopropane carboxylic acid derivatives | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-04-02 | — | — | US | disclosed |
| US-4622337-A | INSECTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-11-11 | — | — | US | disclosed |
| US-4464391-A | Pesticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-08-07 | — | — | US | disclosed |