Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 4/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 4/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 4/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10975836 | 0.87 | PDK1 (0.43) | ARPDK1PDK2PDK3PDK4 | |
| SCHEMBL10975698 | 0.85 | PDK1 (0.43) | ARPDK1PDK2PDK3PDK4 | |
| SCHEMBL10973969 | 0.76 | AR (0.46) | ARPDK1PDK2PDK3PDK4 | |
| SCHEMBL8519255 | 0.74 | AR (0.36) | AR | |
| SCHEMBL8519767 | 0.72 | AR (0.38) | ARPDK1PDK2PDK3PDK4 | |
| SCHEMBL10975133 | 0.72 | AR (0.47) | ARPDK1PDK2PDK3PDK4 | |
| SCHEMBL10974586 | 0.70 | PDK1 (0.44) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL10984328 | 0.70 | AR (0.34) | ARPDK1PDK2PDK3PDK4 | |
| SCHEMBL10974442 | 0.69 | AR (0.32) | ARPDK1PDK2PDK3PDK4 | |
| SCHEMBL8519615 | 0.67 | KDM4E (0.36) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002892-B1 | AMIDE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL OR VETERINARY COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-02-06 | — | — | EP | claimed |