Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PPM1B | O75688 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28688859 | 0.84 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1MAPTHTT | |
| SCHEMBL28932262 | 0.77 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1MAPTHTT | |
| SCHEMBL15443062 | 0.76 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1MAPTHTT | |
| SCHEMBL11807272 | 0.76 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1MAPTHTT | |
| SCHEMBL11591761 | 0.76 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1MAPTHTT | |
| SCHEMBL9806822 | 0.76 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1MAPTHTT | |
| SCHEMBL18888 | 0.76 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1MAPTHTT | |
| SCHEMBL1441063 | 0.76 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1MAPTHTT | |
| SCHEMBL28534028 | 0.75 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4282507 | 0.74 | ALDH1A1 (0.69) | ALDH1A1KMT2AMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1984003090-A1 | SUBSTITUTED 1-AZASPIRO AD4.5 BDDECANES AND 1-AZASPIRO AD5.5 BDUNDECANES | STRUPCZEWSKI JOSEPH T (US) | 1984-08-16 | — | — | WO | disclosed |