SCHEMBL11032059

SCHEMBL11032059

O=C(O)CC(COC(=O)OCCOC(=O)OCC(CC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 4/20 0.43
CPA1 P15085 2/20 0.37
CPB1 P15086 1/20 0.37
CPA3 P15088 1/20 0.37
CPB2 Q96IY4 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.34
SLC22A6 Q4U2R8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10987590 0.94 FOLH1 (0.39) FOLH1CPA1CPB1CPA3CPB2
SCHEMBL11032783 0.94 FOLH1 (0.48) FOLH1CPA1CPB1CPA3CPB2
SCHEMBL10996228 0.90 FOLH1 (0.39) FOLH1CPA1CPB1CPA3CPB2
SCHEMBL11034601 0.89 FOLH1 (0.36) FOLH1CPA1CPB1CPA3CPB2
SCHEMBL11254466 0.89 FOLH1 (0.38) FOLH1CPA1CPB1CPA3CPB2
SCHEMBL10990057 0.88 MEN1 (0.35) FOLH1CPA1CPB1CPA3CPB2
SCHEMBL10997987 0.88 MEN1 (0.35) FOLH1CPA1CPB1CPA3CPB2
SCHEMBL11260611 0.86 ALDH1A1 (0.41) FOLH1TDP1
SCHEMBL11263355 0.84 NAAA (0.41)
SCHEMBL10992828 0.84 FOLH1 (0.35) FOLH1CPA1CPB1CPA3CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4499057-A USING 2,3-DIOXYCARBONYLPROPYL CARBONATES; HYDROMETALLURGY SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1985-02-12 US disclosed
US-4423235-A EXTRACTION AGENTS FOR HYDROMETALLURGY SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1983-12-27 US disclosed