Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | ATM | Q13315 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PARG | Q86W56 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5812323 | 0.83 | PARG (0.62) | ALDH1A1ATMKDM4ETDP1MAPT | |
| SCHEMBL1479993 | 0.81 | ALDH1A1 (0.56) | ALDH1A1ATMKDM4ETDP1MAPT | |
| SCHEMBL813086 | 0.81 | ALDH1A1 (0.56) | ALDH1A1ATMKDM4ETDP1MAPT | |
| SCHEMBL20254153 | 0.80 | ALDH1A1 (0.55) | ALDH1A1ATMKDM4ETDP1MAPT | |
| SCHEMBL8648589 | 0.80 | CYP2C19 (0.45) | ALDH1A1ATMKDM4ETDP1MAPT | |
| SCHEMBL8648590 | 0.80 | CYP2C19 (0.45) | ALDH1A1ATMKDM4ETDP1MAPT | |
| SCHEMBL349527 | 0.78 | MAPT (0.66) | ALDH1A1ATMKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6497984 | 0.77 | CYP2C19 (0.43) | ALDH1A1ATMKDM4ETDP1MAPT | |
| SCHEMBL1409511 | 0.77 | DUT (0.49) | ALDH1A1ATMKDM4ETDP1MAPT | |
| SCHEMBL25767750 | 0.76 | ALDH1A1 (0.50) | ALDH1A1ATMKDM4ETDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0093765-A4 | 2-HYDROXYPROPYLAMINE ARYL ESTER DERIVATIVES. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1984-04-27 | — | — | EP | disclosed |
| EP-0093765-A1 | 2-HYDROXYPROPYLAMINE ARYL ESTER DERIVATIVES. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1983-11-16 | — | — | EP | disclosed |
| WO-1983001770-A1 | 2-HYDROXYPROPYLAMINE ARYL ESTER DERIVATIVES | AMERICAN HOSPITAL SUPPLY CORP (US) | 1983-05-26 | — | — | WO | disclosed |