Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269425 | 0.92 | MAPT (0.58) | FFAR1KEAP1CA1CA2HDAC3 | |
| SCHEMBL11134916 | 0.92 | MAPT (0.58) | FFAR1KEAP1CA1CA2HDAC3 | |
| SCHEMBL25941287 | 0.89 | FFAR1 (0.65) | FFAR1KEAP1CA1CA2HDAC3 | |
| SCHEMBL4845038 | 0.87 | FFAR1 (0.65) | FFAR1KEAP1CA1CA2SMN1; SMN2 | |
| SCHEMBL11424035 | 0.87 | FFAR1 (0.71) | FFAR1KEAP1CA1CA2HDAC3 | |
| Hydrochloric Acid SCHEMBL11105604 | 0.85 | FFAR1 (0.63) | FFAR1KEAP1CA1CA2SMN1; SMN2 | |
| SCHEMBL7827706 | 0.85 | MAPT (0.69) | FFAR1KEAP1CA1CA2HDAC3 | |
| SCHEMBL69746 | 0.84 | FFAR1 (0.81) | FFAR1KEAP1CA1CA2HDAC3 | |
| Glutarate SCHEMBL4744748 | 0.84 | HDAC3 (0.74) | FFAR1KEAP1HDAC3HDAC4HDAC1 | |
| SCHEMBL11135780 | 0.84 | MAPT (0.63) | FFAR1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536391-A | REACTING A PLASMIN HEAVY CHAIN WITH UROKINASE IN THE PRESENCE OF A COUPLING AGENT | OTSUKA PHARMACEUTICAL CO. (JP) | 1985-08-20 | — | — | US | disclosed |
| EP-0109653-A2 | Process for preparing urokinase complex | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-05-30 | — | — | EP | disclosed |