Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11134916 | 1.00 | MAPT (0.58) | MAPTRXFP1FFAR1MAOAKEAP1 | |
| SCHEMBL25941287 | 0.93 | FFAR1 (0.65) | MAPTRXFP1FFAR1MAOAKEAP1 | |
| SCHEMBL11135780 | 0.92 | MAPT (0.63) | MAPTRXFP1FFAR1MAOASLC6A3 | |
| SCHEMBL11032273 | 0.92 | FFAR1 (0.61) | MAPTRXFP1FFAR1KEAP1SLC6A3 | |
| SCHEMBL7827706 | 0.90 | MAPT (0.69) | MAPTRXFP1FFAR1KEAP1SLC6A3 | |
| SCHEMBL11131939 | 0.85 | HRH1 (0.50) | MAPTRXFP1MAOAALDH1A1LMNA | |
| SCHEMBL11137338 | 0.85 | ALDH1A1 (0.65) | MAPTRXFP1MAOASLC6A3MEN1 | |
| SCHEMBL11134216 | 0.84 | HDAC3 (0.54) | MAPTRXFP1FFAR1KEAP1SLC6A3 | |
| SCHEMBL11134102 | 0.84 | HDAC3 (0.54) | MAPTRXFP1FFAR1KEAP1SLC6A3 | |
| SCHEMBL11133284 | 0.84 | HDAC3 (0.54) | MAPTRXFP1FFAR1KEAP1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044541-A1 | Aminocarboxylic acids, amino alcohols, or the derivatives thereof, processes for production thereof, and pharmaceutical composition, containing at least one of these compounds | TEIJIN LIMITED (JP) | 1982-01-27 | — | — | EP | disclosed |