Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.74 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.74 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.74 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.74 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.74 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.74 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.74 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.74 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.74 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.74 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.69 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gamma-Aminobutyric Acid SCHEMBL27597368 | 0.96 | HDAC3 (0.74) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Oxalic Acid SCHEMBL28079977 | 0.86 | MAOA (0.68) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Phenylbutanoic Acid SCHEMBL1021513 | 0.86 | HDAC1 (1.00) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Phenylbutanoic Acid SCHEMBL21219015 | 0.86 | HDAC1 (1.00) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Phenylbutanoic Acid SCHEMBL1716 | 0.86 | HDAC1 (1.00) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Phenylbutanoic Acid SCHEMBL724890 | 0.85 | HDAC1 (0.81) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL11032273 | 0.84 | FFAR1 (0.61) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Acetic Acid SCHEMBL8589684 | 0.84 | MAOA (0.65) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Phenylbutanoic Acid SCHEMBL2010634 | 0.84 | HDAC1 (0.95) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Phenylbutanoic Acid SCHEMBL726614 | 0.84 | HDAC1 (0.95) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008118423-A1 | COMPOSITIONS AND METHODS FOR TREATING MEDICAL CONDITIONS | COMBINATORX, INCORPORATED (US) | 2008-10-02 | — | — | WO | disclosed |