SCHEMBL11032384

SCHEMBL11032384

CCCOC(OCCC)P(=O)(O)O

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FDPS P14324 8/20 0.43
LAP3 P28838 1/20 0.37
LPAR3 Q9UBY5 6/20 0.37
LPAR2 Q9HBW0 3/20 0.37
LPAR1 Q92633 2/20 0.37
METAP1 P53582 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10344098 0.80 FDPS (0.43) FDPSLAP3LPAR3LPAR2LPAR1
SCHEMBL6951134 0.79 MEN1 (0.52) FDPSLAP3
SCHEMBL10448173 0.78 FDPS (0.32) FDPS
SCHEMBL6360402 0.72 CYP1A2 (0.74)
SCHEMBL28464816 0.71 FDPS (0.33) FDPSLPAR3LPAR2LPAR1
SCHEMBL2046370 0.70 SMPD1 (0.42) FDPSLPAR3LPAR2LPAR1METAP1
SCHEMBL20606621 0.70 FDPS (0.34) FDPSLPAR3LPAR2LPAR1METAP1
SCHEMBL2522276 0.70 METAP1 (0.36) FDPSLPAR3LPAR2LPAR1METAP1
Phosphoric Acid SCHEMBL27881840 0.69 LAP3 (0.37) FDPSLAP3LPAR3LPAR2LPAR1
SCHEMBL2048023 0.69 SMPD1 (0.50) FDPSLAP3LPAR3LPAR2LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0050778-B1 PROCESS FOR THE PREPARATION OF PHOSPHONOFORMALDEHYDE-HYDRATE BAYER AG (DE) 1984-06-20 EP disclosed
US-4447367-A Phosphonoformaldehyde, a process for its preparation and its use as an intermediate product for the preparation of medicaments BAYER AKTIENGESELLSCHAFT (DE) 1984-05-08 US disclosed
US-4348332-A Phosphonoformaldehyde, a process for its preparation and its use as an intermediate product for the preparation of medicaments BAYER AKTIENGESELLSCHAFT (DE) 1982-09-07 US disclosed
EP-0050778-A1 Process for the preparation of phosphonoformaldehyde-hydrate BAYER AG (DE) 1982-05-05 EP disclosed