Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753853 | 0.84 | KMT2A (0.45) | HTTKMT2APKMCHRM1 | |
| SCHEMBL27748816 | 0.82 | EPHX2 (0.44) | HTTKMT2APKMALDH1A1CHRM1 | |
| SCHEMBL2760109 | 0.80 | HTT (0.77) | HTTSMN1; SMN2KMT2AMEN1PKM | |
| SCHEMBL4500837 | 0.79 | KMT2A (0.41) | HTTSMN1; SMN2KMT2A | |
| SCHEMBL13160340 | 0.79 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL10673469 | 0.79 | KMT2A (0.46) | HTTKMT2A | |
| SCHEMBL1446597 | 0.78 | HTT (0.64) | HTTSMN1; SMN2KMT2AMEN1PKM | |
| SCHEMBL10750878 | 0.78 | HTT (0.64) | HTTSMN1; SMN2KMT2AMEN1PKM | |
| SCHEMBL1446599 | 0.78 | HTT (0.64) | HTTSMN1; SMN2KMT2AMEN1PKM | |
| SCHEMBL13451654 | 0.77 | HTT (0.63) | HTTSMN1; SMN2KMT2AMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0093765-A4 | 2-HYDROXYPROPYLAMINE ARYL ESTER DERIVATIVES. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1984-04-27 | — | — | EP | disclosed |
| EP-0093765-A1 | 2-HYDROXYPROPYLAMINE ARYL ESTER DERIVATIVES. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1983-11-16 | — | — | EP | disclosed |
| WO-1983001770-A1 | 2-HYDROXYPROPYLAMINE ARYL ESTER DERIVATIVES | AMERICAN HOSPITAL SUPPLY CORP (US) | 1983-05-26 | — | — | WO | disclosed |