Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 3/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.71 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.71 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.71 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.71 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.71 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.57 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.56 |
| ▸ | PLD2 | O14939 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11033995 | 0.99 | ADRA1D (0.72) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL10414989 | 0.92 | ADRA1D (0.68) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL11427976 | 0.91 | ADRA1D (0.77) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL11034160 | 0.91 | ADRA1D (0.66) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL11443065 | 0.90 | ADRA1D (0.73) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL11443046 | 0.89 | ADRA1D (0.83) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL11438152 | 0.89 | ADRA1D (0.84) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL11443041 | 0.87 | ADRA1D (0.74) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL10416818 | 0.87 | ADRA1D (0.69) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL11032713 | 0.85 | ADRA1A (0.63) | ADRA1DADRA1AADRA1BADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446141-A | Hypotensive piperidine derivatives | KYOWA HAKKO KOGYO CO. (JP) | 1984-05-01 | — | — | US | disclosed |
| EP-0018417-A1 | Novel piperidine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD (JP) | 1980-11-12 | — | — | EP | disclosed |