SCHEMBL11033197

SCHEMBL11033197

CC(C)C(=O)c1ccccc1S(N)(=O)=O

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 P00915 15/20 0.59
CA2 P00918 15/20 0.59
CA9 Q16790 11/20 0.59
CA5A P35218 3/20 0.59
CA6 P23280 3/20 0.44
CA4 P22748 2/20 0.44
CYP2C9 P11712 2/20 0.44
CA12 O43570 2/20 0.44
CA7 P43166 2/20 0.44
CA5B Q9Y2D0 2/20 0.44
CA14 Q9ULX7 1/20 0.44
MCL1 Q07820 1/20 0.42
HSD17B10 Q99714 1/20 0.42
LDHA P00338 1/20 0.39
CDK2 P24941 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30849592 0.83 MYC (0.41) CA1CA2CA9CA5ACA12
SCHEMBL6852698 0.83 MYC (0.41) CA1CA2CA9CA5ACA12
SCHEMBL27475173 0.79 MMP2 (0.49)
SCHEMBL31598835 0.79 CA1 (0.65) CA1CA2CA9CA5ACA6
SCHEMBL2511276 0.79 CA1 (0.65) CA1CA2CA9CA5ACA6
SCHEMBL386092 0.78 CA1 (0.61) CA1CA2CA9CA5ACA6
SCHEMBL8925494 0.77 CA1 (0.65) CA1CA2CA9CA5ACA12
SCHEMBL251610 0.77 CA1 (0.51) CA1CA2CA9CA5ACA6
SCHEMBL20646732 0.77 CA1 (0.45) CA1CA2CA9CA5ACA12
SCHEMBL8507951 0.77 CA1 (0.68) CA1CA2CA9CA5ACA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4495365-A N-Acylsulfonamide herbicidal antidotes STAUFFER CHEMICAL CO. (US) 1985-01-22 US disclosed
US-4347380-A N-Acylsulfonamide herbicidal antidotes STAUFFER CHEMICAL COMPANY (US) 1982-08-31 US disclosed