Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 13/20 | 0.65 |
| ▸ | CA2 | P00918 | 13/20 | 0.65 |
| ▸ | CA9 | Q16790 | 10/20 | 0.65 |
| ▸ | CA5A | P35218 | 3/20 | 0.65 |
| ▸ | CA6 | P23280 | 3/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31598835 | 1.00 | CA1 (0.65) | CA1CA2CA9CA5ACA6 | |
| SCHEMBL10438402 | 0.82 | CA2 (0.50) | CA1CA2CA9CA5ACA6 | |
| SCHEMBL10589319 | 0.82 | CA2 (0.58) | CA1CA2CA9CA5ACA6 | |
| SCHEMBL722597 | 0.81 | BCAT2 (0.44) | CA1CA2CA9CA5ACA12 | |
| SCHEMBL353392 | 0.81 | CA1 (0.63) | CA1CA2CA9CA5ACA6 | |
| SCHEMBL353738 | 0.81 | CA1 (0.63) | CA1CA2CA9CA5ACA6 | |
| SCHEMBL31191409 | 0.81 | CA1 (0.63) | CA1CA2CA9CA5ACA6 | |
| SCHEMBL30455577 | 0.81 | BCAT2 (0.62) | CA1CA2CA9CA5AKDM4E | |
| SCHEMBL6631818 | 0.81 | BCAT2 (0.62) | CA1CA2CA9CA5AKDM4E | |
| Hydrochloric Acid SCHEMBL7552816 | 0.79 | BCAT2 (0.43) | CA1CA2CA9CA5ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104953034-B | Degradable base board for flexible optoelectronic part and preparation method thereof | 电子科技大学 | 2018-03-13 | — | — | CN | claimed |
| CN-106588742-A | Pyroglutamic acid-derived hydrogen-bonding organic catalyst and its preparation method and application | 中南大学 | 2017-04-26 | — | — | CN | claimed |
| CN-106452100-A | Three-level photovoltaic grid-connected inverter based on DSP control and working method of three-level photovoltaic grid-connected inverter | 江苏建筑职业技术学院 | 2017-02-22 | — | — | CN | claimed |
| US-20230082167-A1 | NOVEL TRICYCLIC COMPOUNDS | ABBVIE INC (US) | 2023-03-16 | — | — | US | disclosed |
| CN-110357824-A | [3,5- di-substituted-phenyl -1- (1,2,4- triazol radical)] benzene sulfonic derivative and preparation method and application | 中山大学 | 2019-10-22 | — | — | CN | disclosed |
| CN-106588742-B | Hydrogen bond organic catalyst derived from a kind of pyroglutamic acid and its preparation method and application | 中南大学 | 2018-11-30 | — | — | CN | disclosed |
| US-20180291029-A1 | NOVEL TRICYCLIC COMPOUNDS | ABBVIE INC. (US) | 2018-10-11 | — | — | US | disclosed |
| CN-104395262-B | Powdery accelerator | 建筑研究和技术有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-106831648-A | The synthetic method of diazoxiide | 北京同济达药业有限公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-106588742-A | Pyroglutamic acid-derived hydrogen-bonding organic catalyst and its preparation method and application | 中南大学 | 2017-04-26 | — | — | CN | disclosed |
| CN-106521411-A | DEPOSITION MASK AND METHOD OF FABRICATING THE SAME | 三星显示有限公司 | 2017-03-22 | — | — | CN | disclosed |
| US-8541407-B2 | Substituted benzo-pyrido-triazolo-diazepine compounds | ARQULE, INC. (US) | 2013-09-24 | — | — | US | disclosed |
| US-20120245138-A1 | N-(2-(HETARYL)ARYL)ARYLSULFONAMIDES AND N-(2-(HETARYL)HETARYL ARYLSULFONAMIDES | CHEMOCENTRYX, INC. (US) | 2012-09-27 | — | — | US | disclosed |
| CN-102245543-A | Low-molecular compound, polymer, electronic device material, composition for electronic device, organic electroluminescent element, organic solar cell element, display device, and lighting device | MITSUBISHI CHEM CORP | 2011-11-16 | — | — | CN | disclosed |
| US-20110245236-A1 | Substituted Benzo-Pyrido-Triazolo-Diazepine Compounds | ARQULE, INC. (US) | 2011-10-06 | — | — | US | disclosed |
| US-20100331302-A1 | N-(2-(HETARYL)ARYL) ARYLSULFONAMIDES AND N-(2-(HETARYL)HETARYL ARYLSULFONAMIDES | CHEMOCENTRYX, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-7776877-B2 | N-(4-Chloro-2-[1,2,3]triazolo[4,5-b]pyridin-1-yl-phenyl)-4-(1-hydroxy-1-methyl-ethyl)-benzene-sulfonamide sodium salt, used as chemokine receptors antagonists, useful for treating inflammation | CHEMOCENTRYX, INC. (US) | 2010-08-17 | — | — | US | disclosed |
| US-20090312338-A1 | Novel Tricyclic Compounds | ABBOTT LABORATORIES (US) | 2009-12-17 | — | — | US | disclosed |
| US-20090005410-A1 | N-(4-Chloro-2-[1,2,3]triazolo[4,5-b]pyridin-1-yl-phenyl)-4-(1-hydroxy-1-methyl-ethyl)-benzene-sulfonamide sodium salt, used as chemokine receptors antagonists, useful for treating inflammation | CHEMOCENTRYX, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| US-7189848-B2 | Substituted sulfonylaminomethylbenzoic acid (derivatives) and their preparation | BAYER CROPSCIENCE GMBH (DE) | 2007-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331302-A1 | N-(2-(HETARYL)ARYL) ARYLSULFONAMIDES AND N-(2-(HETARYL)HETARYL ARYLSULFONAMIDES | CCR9, CCR2, CCR10 | CA1 4778/4885CA2 4258/4885CA9 1132/4885 |
| US-20110245236-A1 | Substituted Benzo-Pyrido-Triazolo-Diazepine Compounds | BRD4, PDXK, THPO | CA1 3942/4885CA2 3163/4885CA9 3726/4885 |
| US-20120245138-A1 | N-(2-(HETARYL)ARYL)ARYLSULFONAMIDES AND N-(2-(HETARYL)HETARYL ARYLSULFONAMIDES | CCR9, CCR2, CCR10 | CA1 4778/4885CA2 4258/4885CA9 1132/4885 |
| US-20180291029-A1 | NOVEL TRICYCLIC COMPOUNDS | CYP11B2, CYP11B1, ABCB1 | CA1 1741/4885CA2 1885/4885CA9 881/4885 |
| US-20090312338-A1 | Novel Tricyclic Compounds | CYP11B2, CYP11B1, ABCB1 | CA1 1741/4885CA2 1885/4885CA9 881/4885 |
| US-20090005410-A1 | N-(4-Chloro-2-[1,2,3]triazolo[4,5-b]pyridin-1-yl-phenyl)-4-(1-hydroxy-1-methyl-ethyl)-benzene-sulfonamide sodium salt, used as chemokine receptors antagonists, useful for treating inflammation | CCR9, CCR1, CCR2 | CA1 2546/4885CA2 1216/4885CA9 300/4885 |
| US-20230082167-A1 | NOVEL TRICYCLIC COMPOUNDS | CYP11B2, CYP11B1, ABCB1 | CA1 1741/4885CA2 1885/4885CA9 881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.