Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ESRRA | P11474 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11031492 | 0.92 | LMNA (0.58) | LMNAMAPTESRRAGAAHPGD | |
| SCHEMBL17351270 | 0.85 | HPGD (0.67) | LMNAMAPTGAAHPGDKMT2A | |
| SCHEMBL10756271 | 0.82 | S1PR4 (0.56) | LMNAMAPTGAAHPGDMAPK1 | |
| SCHEMBL10962765 | 0.81 | MAPT (0.56) | LMNAMAPTESRRAGAAHPGD | |
| SCHEMBL11028620 | 0.80 | MAPT (0.53) | LMNAMAPTESRRAGAAHPGD | |
| SCHEMBL8657564 | 0.79 | LMNA (0.52) | LMNAMAPTESRRAGAAHPGD | |
| SCHEMBL10770531 | 0.78 | HPGD (0.40) | LMNAMAPTGAAHPGDKMT2A | |
| SCHEMBL10963006 | 0.77 | MAPT (0.50) | LMNAMAPTESRRAGAAHPGD | |
| SCHEMBL10962726 | 0.76 | ESRRA (0.49) | LMNAMAPTESRRAHPGDKMT2A | |
| SCHEMBL11030421 | 0.75 | MAPT (0.48) | LMNAMAPTESRRAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426385-A | Insecticidal bicyclooxyphenyl ureas | UNION CARBIDE CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |
| EP-0050321-A2 | Novel bicyclooxyphenyl ureas, process for their preparation and pesticides containing them | UNION CARBIDE CORPORATION (US) | 1982-04-28 | — | — | EP | disclosed |