Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.46 |
| ▸ | CBR1 | P16152 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17351244 | 0.87 | PDE7A (0.52) | S1PR4TDP1TSHRMAPK1LMNA | |
| SCHEMBL17351270 | 0.85 | HPGD (0.67) | S1PR4TDP1MAPK1LMNAPOLB | |
| SCHEMBL9332087 | 0.84 | TDP1 (0.66) | S1PR4TDP1TSHRMAPK1LMNA | |
| SCHEMBL3654191 | 0.84 | PDE7A (0.63) | S1PR4TDP1TSHRMAPK1LMNA | |
| SCHEMBL20855342 | 0.84 | S1PR4 (0.73) | S1PR4TDP1TSHRMAPK1LMNA | |
| SCHEMBL15330302 | 0.84 | PDE7A (0.52) | S1PR4TDP1TSHRMAPK1LMNA | |
| SCHEMBL4965836 | 0.83 | MAPK1 (0.62) | S1PR4TDP1TSHRMAPK1LMNA | |
| SCHEMBL11033209 | 0.82 | LMNA (0.58) | S1PR4TSHRMAPK1LMNAPOLB | |
| SCHEMBL10770531 | 0.81 | HPGD (0.40) | S1PR4TDP1MAPK1LMNAPOLB | |
| SCHEMBL11159166 | 0.81 | PDE7A (0.52) | S1PR4TDP1TSHRLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215056-A1 | PESTICIDAL 1-(4-PHENOXYPHENYL)-3-BENZOYL UREA COMPOUNDS AND PROCESS FOR PREPARATION | UNION CARBIDE CORPORATION (US) | 1987-03-25 | — | — | EP | disclosed |
| WO-1986005781-A1 | PESTICIDAL 1-(4-PHENOXYPHENYL)-3-BENZOYL UREA COMPOUNDS AND PROCESS FOR PREPARATION | UNION CARBIDE CORPORATION (US) | 1986-10-09 | — | — | WO | disclosed |