SCHEMBL11033239

SCHEMBL11033239

CCCSP(=O)(OCC)Oc1ccc(C=O)c(OC)c1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
L3MBTL1 Q9Y468 1/20 0.41
MAOB P27338 2/20 0.36
ERN1 O75460 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP1B1 Q16678 1/20 0.36
ROCK2 O75116 1/20 0.35
ROCK1 Q13464 1/20 0.35
KDM4E B2RXH2 1/20 0.35
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11299547 0.82 ALDH1A1 (0.43) ALDH1A1MEN1KMT2ATSHR
SCHEMBL11299555 0.80 MAPK1 (0.34) MEN1KMT2A
SCHEMBL11299550 0.79 MEN1 (0.33) MEN1KMT2A
SCHEMBL11033494 0.79 SRC (0.48) ALDH1A1
SCHEMBL11033731 0.78 ALDH1A1 (0.39) ALDH1A1
SCHEMBL11033080 0.78 CA1 (0.39) ALDH1A1MEN1KMT2AKDM4ETSHR
SCHEMBL11761263 0.77 KCNH2 (0.36) ALDH1A1TSHR
SCHEMBL11215664 0.77 SRC (0.50) MAOBTDP1
SCHEMBL11031581 0.75 CYP2C19 (0.37)
SCHEMBL11794980 0.74 JUN (0.38) MEN1KMT2ACYP1A1CYP1A2CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4436736-A INSECTICIDES, MITICIDES UNION CARBIDE CORPORATION (US) 1984-03-13 US disclosed