Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 5/20 | 0.68 |
| ▸ | FKBP1A | P62942 | 7/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228388 | 0.91 | PREP (0.71) | PREPFKBP1AACEALDH1A1KMT2A | |
| SCHEMBL11764594 | 0.91 | PREP (0.71) | PREPFKBP1AACEALDH1A1KMT2A | |
| SCHEMBL18620837 | 0.90 | PREP (0.67) | PREPFKBP1AACEALDH1A1CYP3A4 | |
| SCHEMBL9464405 | 0.90 | PREP (0.67) | PREPFKBP1AACEALDH1A1CYP3A4 | |
| SCHEMBL2082597 | 0.90 | PREP (0.69) | PREPFKBP1AACEALDH1A1KMT2A | |
| SCHEMBL9518270 | 0.89 | PREP (0.68) | PREPFKBP1AACEALDH1A1KMT2A | |
| SCHEMBL7295710 | 0.88 | PREP (0.62) | PREPFKBP1AACEALDH1A1CYP3A4 | |
| SCHEMBL17576527 | 0.88 | PREP (0.64) | PREPFKBP1AACEALDH1A1KMT2A | |
| SCHEMBL21132738 | 0.88 | PREP (0.64) | PREPFKBP1AACEALDH1A1KMT2A | |
| SCHEMBL11761001 | 0.88 | PREP (0.67) | PREPFKBP1AACEALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60172929-A | — | — | None | — | — | JP | disclosed |
| EP-2987794-B1 | VINBLASTINE DERIVATIVES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | UNIV JINAN (CN) | 2018-05-30 | — | — | EP | disclosed |
| US-20160068552-A1 | VINBLASTINE DERIVATIVES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | JINAN UNIVERSITY (CN) | 2016-03-10 | — | — | US | disclosed |
| JP-S60172929-A | AGENT FOR ALLEVIATING AMNESIA | YAKULT HONSHA CO LTD | 1985-09-06 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160068552-A1 | VINBLASTINE DERIVATIVES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | WEE1, WEE2, VIP | PREP 47/4885FKBP1A 1966/4885ACE 2100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.