Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.71 |
| ▸ | ACE | P12821 | 8/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11764594 | 1.00 | PREP (0.71) | PREPACEALDH1A1FKBP1AACE2 | |
| SCHEMBL13471059 | 0.97 | PREP (0.67) | PREPACEALDH1A1FKBP1AACE2 | |
| SCHEMBL11761001 | 0.97 | PREP (0.67) | PREPACEALDH1A1FKBP1AACE2 | |
| SCHEMBL11760983 | 0.97 | PREP (0.67) | PREPACEALDH1A1FKBP1AACE2 | |
| SCHEMBL8258772 | 0.96 | PREP (0.66) | PREPACEALDH1A1FKBP1AACE2 | |
| SCHEMBL4244330 | 0.96 | PREP (0.66) | PREPACEALDH1A1FKBP1AACE2 | |
| SCHEMBL2082597 | 0.92 | PREP (0.69) | PREPACEALDH1A1FKBP1AKMT2A | |
| SCHEMBL11033242 | 0.91 | PREP (0.68) | PREPACEALDH1A1FKBP1AKMT2A | |
| SCHEMBL9518270 | 0.91 | PREP (0.68) | PREPACEALDH1A1FKBP1AKMT2A | |
| SCHEMBL9464405 | 0.90 | PREP (0.67) | PREPACEALDH1A1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567566-B | Liquid phase synthesis process of cyclohexapeptide-9 | 山东济肽生物科技有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117567566-A | Liquid phase synthesis process of cyclohexapeptide-9 | 山东济肽生物科技有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-116549596-A | Application of vinblastine derivative in preparation of medicines for treating lymph node metastasis | 暨南大学 | 2023-08-08 | — | — | CN | claimed |
| CN-113929739-B | Gly-Pro-Arg-Pro-NH ethoxycarbonyl warfarin, synthesis, activity and application thereof | 首都医科大学 | 2023-07-28 | — | — | CN | claimed |
| CN-114195676-B | Biarylhydrazine compound and adduct thereof and application of compound in preparation of antitumor drugs | 广州药本君安医药科技股份有限公司 | 2022-08-05 | — | — | CN | claimed |
| CN-114656520-A | Prolinamide endopeptidase near-infrared fluorescent probe substrate, and preparation method and application thereof | 上海中医药大学 | 2022-06-24 | — | — | CN | claimed |
| CN-114195676-A | Biarylhydrazine compound and adduct thereof and application of compound in preparation of antitumor drugs | 广州药本君安医药科技股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-113845563-A | FAP alpha enzyme activated podophyllotoxin derivative and preparation method and application thereof | 遵义医药高等专科学校 | 2021-12-28 | — | — | CN | claimed |
| CN-113456797-A | Application of vinblastine derivative in preparation of medicine for treating osteosarcoma and/or soft tissue sarcoma | 暨南大学 | 2021-10-01 | — | — | CN | claimed |
| US-10377774-B2 | Vinblastine derivatives, preparation method therefor and application thereof | JINAN UNIVERSITY (CN) | 2019-08-13 | — | — | US | claimed |
| EP-2987794-B1 | VINBLASTINE DERIVATIVES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | UNIV JINAN (CN) | 2018-05-30 | — | — | EP | claimed |
| EP-2987794-A1 | VINBLASTINE DERIVATIVES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Jinan University (CN) | 2016-02-24 | — | — | EP | claimed |
| US-20020147317-A1 | Fluorogenic compounds and uses therefor | 3M INNOVATIVE PROPETIES COMPANY | 2002-10-10 | — | — | US | claimed |
| US-6372895-B1 | USEFUL IN ASSAYING FOR BIOLOGICAL ACTIVITY | 3M INNOVATIVE PROPERTIES COMPANY | 2002-04-16 | — | — | US | claimed |
| EP-0416282-B1 | Microbiologically produced N-Acyl-L-proline-acylase, process for its production and its use | DEGUSSA (DE) | 1994-09-14 | — | — | EP | claimed |
| US-5219741-A | Reacting in the presence of microbiologically produced N-acyl-L-proline acylase | DEGUSSA AG (DE) | 1993-06-15 | — | — | US | claimed |
| US-5120652-A | Synthesis of proline from acyl derivatives; thermostable | DEGUSSA AG (DE) | 1992-06-09 | — | — | US | claimed |
| EP-0416282-A1 | Microbiologically produced N-Acyl-L-proline-acylase, process for its production and its use | Degussa Aktiengesellschaft (DE) | 1991-03-13 | — | — | EP | claimed |
| JP-1074987-A | — | — | None | — | — | JP | disclosed |
| JP-S06474987-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147317-A1 | Fluorogenic compounds and uses therefor | NOTUM, WEE1, CPSF7 | PREP 246/4885ACE 2808/4885ALDH1A1 762/4885 |
| US-10377774-B2 | Vinblastine derivatives, preparation method therefor and application thereof | WEE1, WEE2, VIP | PREP 47/4885ACE 2100/4885ALDH1A1 1008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.