SCHEMBL9464405

SCHEMBL9464405

COC(=O)[C@@H]1CCCN1C(=O)CNC(=O)OCc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PREP P48147 3/20 0.67
ALDH1A1 P00352 2/20 0.59
CYP3A4 P08684 1/20 0.59
TSHR P16473 1/20 0.59
FKBP1A P62942 9/20 0.58
ACE P12821 3/20 0.52
KLK5 Q9Y337 1/20 0.52
NPSR1 Q6W5P4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18620837 1.00 PREP (0.67) PREPALDH1A1CYP3A4TSHRFKBP1A
SCHEMBL1189713 0.97 FKBP1A (0.63) PREPALDH1A1CYP3A4TSHRFKBP1A
SCHEMBL2082597 0.93 PREP (0.69) PREPALDH1A1CYP3A4TSHRFKBP1A
SCHEMBL11033242 0.90 PREP (0.68) PREPALDH1A1CYP3A4TSHRFKBP1A
SCHEMBL11764594 0.90 PREP (0.71) PREPALDH1A1FKBP1AACE
SCHEMBL2228388 0.90 PREP (0.71) PREPALDH1A1FKBP1AACE
SCHEMBL7295710 0.89 PREP (0.62) PREPALDH1A1CYP3A4TSHRFKBP1A
SCHEMBL22811435 0.89 PREP (0.53) PREPALDH1A1CYP3A4TSHRFKBP1A
SCHEMBL22811113 0.88 PREP (0.52) PREPALDH1A1CYP3A4TSHRFKBP1A
SCHEMBL9518270 0.88 PREP (0.68) PREPALDH1A1CYP3A4TSHRFKBP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116655729-A BPA oligomer and targeting compound thereof, preparation method and application 重庆高硼生物科技有限公司 2023-08-29 CN disclosed
WO-2015181186-A1 1 -(CYCLOPENT-2-EN-1 -YL)-3-(2-HYDROXY-3-(ARYLSULFONYL)PHENYL)UREA DERIVATIVES AS CXCR2 INHIBITORS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2015-12-03 WO disclosed
EP-0294667-B1 (2-CYANO-2-OXIMINOACETYL)-AMINO ACID DERIVATIVES BAYER AG (DE) 1993-03-17 EP disclosed
US-5189061-A Fungicide BAYER AKTIENGESELLSCHAFT (DE) 1993-02-23 US disclosed
US-5026710-A Fungicides BAYER AKTIENGESELLSCHAFT (DE) 1991-06-25 US disclosed
US-4963548-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1990-10-16 US disclosed