Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL707497 | 0.91 | LTA4H (0.43) | TLR8LTA4HCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7120587 | 0.89 | LTA4H (0.39) | TLR8TLR2LTA4HMEN1KMT2A | |
| SCHEMBL710735 | 0.87 | LTA4H (0.43) | TLR8LTA4HCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL702248 | 0.87 | LTA4H (0.43) | TLR8LTA4HCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4738095 | 0.86 | TLR8 (0.33) | TLR8TLR2LTA4HCYP1A2CYP2C9 | |
| SCHEMBL706144 | 0.85 | LTA4H (0.44) | TLR8LTA4HCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19470870 | 0.84 | LTA4H (0.39) | LTA4HALDH1A1TSHR | |
| SCHEMBL19470873 | 0.84 | LTA4H (0.39) | LTA4HALDH1A1TSHR | |
| SCHEMBL20483518 | 0.84 | LTA4H (0.39) | LTA4HALDH1A1TSHR | |
| SCHEMBL19470862 | 0.84 | LTA4H (0.39) | LTA4HALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4477496-A | AN ORGANO-SILANE COUPLING AGENT, AND AN EPOXIDIZED POLYMER REACTED WITH AN AMINO ORGANO-SILANE COMPOUND | PPG INDUSTRIES, INC. (US) | 1984-10-16 | — | — | US | disclosed |
| US-4457970-A | Glass fiber reinforced thermoplastics | PPG INDUSTRIES, INC. (US) | 1984-07-03 | — | — | US | disclosed |
| US-4435474-A | PRODUCT OF EPOXIDIZED POLYMER AND AMINOSILANE, CROSSLINKABLE POLYMER | PPG INDUSTRIES, INC. (US) | 1984-03-06 | — | — | US | disclosed |
| US-4410645-A | REACTION PRODUCT OF EPOXIDIZED THERMOPLASTIC COPOLYMER AND ORGANOAMINOSILANE | PPG INDUSTRIES, INC. (US) | 1983-10-18 | — | — | US | disclosed |
| US-4338233-A | Aqueous sizing composition and sized glass fibers and method | PPG INDUSTRIES, INC. (US) | 1982-07-06 | — | — | US | disclosed |
| US-4277284-A | ORGANIC SILICATE WHICH MAY BE PARTIALLY HYDROLYZED AND AN AMINOSILANES CORROSION RESISTANT PRIMERS | UNION CARBIDE CORPORATION (US) | 1981-07-07 | — | — | US | disclosed |
| US-4055701-A | Azido-silane compositions | UNION CARBIDE CORPORATION (US) | 1977-10-25 | — | — | US | disclosed |
| US-4038456-A | AZIDO-SILANE COMPOSITIONS | UNION CARBIDE CORPORATION (US) | 1977-07-26 | — | — | US | disclosed |
| US-4002651-A | Azido-silane compositions | UNION CARBIDE CORPORATION (US) | 1977-01-11 | — | — | US | disclosed |
| US-3944574-A | Azido-silane compositions | UNION CARBIDE CORPORATION (US) | 1976-03-16 | — | — | US | disclosed |