SCHEMBL7120587

SCHEMBL7120587

CCCCCO[Si](CCCN)(OCCCCC)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.39
TLR2 O60603 3/20 0.37
TLR8 Q9NR97 6/20 0.37
LMNA P02545 3/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
TSHR P16473 2/20 0.35
CYP3A4 P08684 2/20 0.35
TP53 P04637 1/20 0.35
MAPK1 P28482 1/20 0.35
ALDH1A1 P00352 1/20 0.34
MEN1 O00255 1/20 0.34
NR1I2 O75469 1/20 0.34
CHRM2 P08172 1/20 0.34
ADRA2A P08913 1/20 0.34
MAPT P10636 1/20 0.34
OPRK1 P41145 1/20 0.34
HTR2B P41595 1/20 0.34
SLC6A3 Q01959 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4738095 0.90 TLR8 (0.33) LTA4HTLR2TLR8LMNAMEN1
SCHEMBL11033252 0.89 TLR8 (0.38) LTA4HTLR2TLR8TSHRALDH1A1
SCHEMBL19809308 0.87 LTA4H (0.43) LTA4HTLR8LMNANPC1RAB9A
SCHEMBL707497 0.85 LTA4H (0.43) LTA4HTLR8LMNANPC1RAB9A
SCHEMBL702248 0.85 LTA4H (0.43) LTA4HTLR8LMNANPC1RAB9A
SCHEMBL710735 0.85 LTA4H (0.43) LTA4HTLR8LMNANPC1RAB9A
SCHEMBL28867246 0.84 LTA4H (0.39) LTA4HLMNANPC1RAB9ASMN1; SMN2
SCHEMBL20483784 0.83 LTA4H (0.40) LTA4HLMNANPC1RAB9ASMN1; SMN2
SCHEMBL1069349 0.83 MAOA (0.34) TLR8
SCHEMBL706144 0.83 LTA4H (0.44) LTA4HTLR8LMNANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0330456-B1 Preparation of silicon-containing polyimide precursor and cured polyimides obtained therefrom CHISSO CORP (JP) 1994-09-07 EP claimed
US-6664021-B1 Acid generator and silicon-containing polyimide ester precursor comprising partially esterified silicon-containing polyamic ester; radiating with light CHISSO CORPORATION (JP) 2003-12-16 US disclosed
EP-0601203-B1 PHOTOSENSITIVE RESIN COMPOSITION CHISSO CORP (JP) 1999-09-29 EP disclosed
EP-0546814-B1 A polyimide photosensitive cover coating agent CHISSO CORP (JP) 1997-09-17 EP disclosed
EP-0456469-B1 Photosensitive heat-resistant polymer having hydroxyphenyl group CHISSO CORP (JP) 1996-08-21 EP disclosed
US-5473040-A A protective coatings comprising a crosslinked terpolymer of polyimide, polysilsesquioxane and polysiloxane; hardness, heat resistance, insulation CHISSO CORPORATION (JP) 1995-12-05 US disclosed
US-5449705-A Silicon-containing polyamic acid derivative and photosensitive resin composition using it CHISSO CORPORATION (JP) 1995-09-12 US disclosed
US-5449588-A Shrinkage inhibition CHISSO CORPORATION (JP) 1995-09-12 US disclosed
US-5442024-A Polyamic acid having a crosslinkable silane group or copolymerized with a polysiloxane and a compound generating an acid catalyst to effect imidation upon radiating; films; photoresists; shrinkage inhibition; resolution; adhesion CHISSO CORPORATION (JP) 1995-08-15 US disclosed
EP-0379377-B1 Process for preparing photosensitive heat-resistant polymer CHISSO CORP (JP) 1995-05-17 EP disclosed
US-5055549-A Using isoimide intermediate CHISSO CORPORATION (JP) 1991-10-08 US disclosed
US-5026788-A Photosensitive polymer having thiol group CHISSO CORPORATION (JP) 1991-06-25 US disclosed
US-5025088-A Photosensitive poly(amide)imide heat-resistant polymer CHISSO CORPORATION (JP) 1991-06-18 US disclosed
US-4963635-A REACTING A FLUORINE-CONTAINING DIANHYDRIDE OR DIANHYDRIDE, A FLUORINE-CONTAINING DIAMINE OR A DEIAMINE AND AN AMINO-CONTAINING OXYSILANE COMPOUND CHISSO CORPORATION (JP) 1990-10-16 US disclosed
EP-0379377-A2 Process for preparing photosensitive heat-resistant polymer Chisso Corporation (JP) 1990-07-25 EP disclosed
EP-0348092-A2 Photosensitive polymer having thiol groups Chisso Corporation (JP) 1989-12-27 EP disclosed
EP-0337698-A2 Photosensitive Polymer Chisso Corporation (JP) 1989-10-18 EP disclosed
EP-0330456-A1 Preparation of silicon-containing polyimide precursor and cured polyimides obtained therefrom CHISSO CORPORATION (JP) 1989-08-30 EP disclosed
US-3950308-A POLYAMIDES, POLYIMIDES, POLYAMIDE-IMIDES CIBA-GEIGY CORPORATION (US) 1976-04-13 US disclosed
US-3948835-A POLYAMIDE, POLYAMIDE-ACID OR POLYAMIDE-AMIDE-ACIDS CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed