Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8785501 | 0.87 | HPGD (0.59) | HPGDALDH1A1HTTKDM4CKDM4E | |
| SCHEMBL14781423 | 0.84 | HTT (0.60) | HPGDALDH1A1HTTKDM4CKDM4E | |
| SCHEMBL11031645 | 0.84 | HPGD (0.56) | HPGDALDH1A1HTTKDM4CKDM4E | |
| SCHEMBL11035162 | 0.84 | HPGD (0.70) | HPGDALDH1A1HTTKDM4CLMNA | |
| SCHEMBL12894766 | 0.76 | HPGD (0.50) | HPGDALDH1A1HTTKDM4CKDM4E | |
| SCHEMBL10750845 | 0.75 | ENPP3 (0.44) | ALDH1A1HTTPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL934859 | 0.74 | HTT (0.71) | HPGDALDH1A1HTTKDM4CKDM4E | |
| SCHEMBL23367845 | 0.74 | KDM4E (0.53) | HPGDALDH1A1HTTKDM4CKDM4E | |
| SCHEMBL11409305 | 0.72 | KMT2A (0.57) | HPGDALDH1A1HTTKDM4CKDM4E | |
| SCHEMBL3030217 | 0.72 | HTT (0.44) | HPGDALDH1A1HTTKDM4CHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438092-A | 5-Amino-N-(3-chloro- 2-methyl-, or 2-fluorophenyl)-1,3-dimethyl-1H-pyrazole-4-carboxamides and use as an anti-convulsant | WARNER-LAMBERT COMPANY (US) | 1984-03-20 | — | — | US | disclosed |
| US-4346097-A | ANTIEPILEPTIC | WARNER-LAMBERT COMPANY (US) | 1982-08-24 | — | — | US | disclosed |