Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8785501 | 0.86 | HPGD (0.59) | HPGDALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL11033378 | 0.84 | HPGD (0.57) | HPGDALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL7463068 | 0.84 | ALDH1A1 (0.55) | HPGDALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL11930692 | 0.84 | ALDH1A1 (0.57) | HPGDALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL14781423 | 0.83 | HTT (0.60) | HPGDALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL11031645 | 0.83 | HPGD (0.56) | HPGDALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL11419852 | 0.83 | HPGD (0.71) | HPGDALDH1A1SMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL4922992 | 0.81 | ALDH1A1 (0.49) | HPGDALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL15579406 | 0.81 | SMN1; SMN2 (0.52) | HPGDALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL4449299 | 0.80 | CHRM3 (0.48) | HPGDALDH1A1SMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438092-A | 5-Amino-N-(3-chloro- 2-methyl-, or 2-fluorophenyl)-1,3-dimethyl-1H-pyrazole-4-carboxamides and use as an anti-convulsant | WARNER-LAMBERT COMPANY (US) | 1984-03-20 | — | — | US | disclosed |
| US-4346097-A | ANTIEPILEPTIC | WARNER-LAMBERT COMPANY (US) | 1982-08-24 | — | — | US | disclosed |