Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | GPX4 | P36969 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | RNF4 | P78317 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9133855 | 0.86 | MTNR1A (0.51) | MTNR1AMTNR1BALDH1A1NPC1RAB9A | |
| SCHEMBL28970975 | 0.85 | KDM4E (0.52) | MTNR1AMTNR1BALDH1A1NPC1RAB9A | |
| SCHEMBL21894115 | 0.83 | MTNR1A (0.55) | MTNR1AMTNR1BESR1SMN1; SMN2 | |
| SCHEMBL9515298 | 0.83 | MTNR1A (0.51) | MTNR1AMTNR1BESR1ALOX15 | |
| SCHEMBL11030800 | 0.82 | HSD17B2 (0.56) | MTNR1AMTNR1B | |
| SCHEMBL28129412 | 0.82 | MTNR1A (0.52) | MTNR1AMTNR1BESR1ALOX15 | |
| SCHEMBL31186740 | 0.80 | ALDH1A1 (0.55) | MTNR1AMTNR1BALDH1A1NPC1RAB9A | |
| SCHEMBL9134008 | 0.80 | MTNR1A (0.46) | MTNR1AMTNR1BALDH1A1NPC1RAB9A | |
| SCHEMBL18338240 | 0.80 | ALDH1A1 (0.70) | ALDH1A1NPC1RAB9APAX8TP53 | |
| SCHEMBL27876348 | 0.79 | ALDH1A1 (0.54) | MTNR1AMTNR1BALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127634-A1 | PYRROLOCOUMARIN DERIVATIVES, THEIR MANUFACTURE AND UTILISATION | KATHOLIEKE UNIVERSITEIT TE LEUVEN (BE) | 1984-12-12 | — | — | EP | disclosed |
| WO-1984002133-A1 | PYRROLOCOUMARIN DERIVATIVES, THEIR MANUFACTURE AND UTILISATION | UNIV LEUVEN KATH (BE) | 1984-06-07 | — | — | WO | disclosed |