Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29664634 | 0.67 | ALOX5 (0.46) | MAPTCES2CES1KMT2APTPN1 | |
| Bicarbonate SCHEMBL28968865 | 0.66 | MAPT (0.49) | MAPTCES2CES1KMT2APTPN1 | |
| SCHEMBL6312514 | 0.66 | MAPT (0.41) | MAPTCES2CES1KMT2AL3MBTL1 | |
| SCHEMBL12674134 | 0.66 | KDM4E (0.40) | MAPTKMT2ATAAR1MEN1ALDH1A1 | |
| SCHEMBL14899622 | 0.66 | KMT2A (0.44) | MAPTCES2CES1KMT2APTPN1 | |
| SCHEMBL11470675 | 0.65 | MAPT (0.44) | MAPTCES2CES1KMT2APOLB | |
| SCHEMBL7629307 | 0.64 | — | — | |
| SCHEMBL13994295 | 0.64 | — | — | |
| SCHEMBL2075002 | 0.64 | PTPN1 (0.42) | MAPTCES2CES1KMT2APTPN1 | |
| SCHEMBL71754 | 0.64 | MAPT (0.42) | MAPTCES2CES1KMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4503052-A | OXACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1985-03-05 | — | — | US | disclosed |