Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4418028 | 0.83 | ALOX5 (0.49) | ALOX5KMT2APOLBPTPN1PKM | |
| SCHEMBL27536602 | 0.79 | KMT2A (0.52) | ALOX5KMT2APOLBPTPN1PKM | |
| SCHEMBL2480787 | 0.78 | KMT2A (0.61) | ALOX5KMT2APOLBPTPN1PKM | |
| SCHEMBL11538261 | 0.78 | KMT2A (0.52) | ALOX5KMT2APOLBPTPN1PKM | |
| SCHEMBL5535025 | 0.77 | ALDH1A1 (0.48) | ALOX5KMT2APOLBPTPN1PKM | |
| Hydrochloric Acid SCHEMBL9402317 | 0.76 | KMT2A (0.59) | ALOX5KMT2APOLBPTPN1PKM | |
| SCHEMBL9402314 | 0.76 | ALOX5 (0.49) | ALOX5KMT2APOLBPTPN1PKM | |
| SCHEMBL3577958 | 0.76 | ALOX5 (0.58) | ALOX5KMT2APOLBPTPN1PKM | |
| SCHEMBL14899622 | 0.75 | KMT2A (0.44) | ALOX5KMT2APOLBPTPN1PKM | |
| Hydrochloric Acid SCHEMBL5352590 | 0.74 | ALOX5 (0.56) | ALOX5KMT2APOLBPTPN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022096679-A1 | PROTEIN-PROTEIN INTERACTION MODULATORS OF AURORA KINASE A AND THEIR USE IN THE PREVENTION AND/OR TREATMENT OF CANCER | EBERHARD KARLS UNIVERSITÄT TÜBINGEN (DE) | 2022-05-12 | — | — | WO | disclosed |