Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.44 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11003895 | 0.79 | LMNA (0.49) | CRBNFKBP5LMNAHSD17B10KDM4E | |
| SCHEMBL10999924 | 0.77 | LMNA (0.40) | CRBNFKBP5LMNAHSD17B10 | |
| SCHEMBL10998655 | 0.76 | HSD17B10 (0.50) | CRBNFKBP5LMNAHSD17B10KDM4E | |
| SCHEMBL11720970 | 0.72 | CRBN (0.50) | CRBNFKBP5LMNAHSD17B10OR51E2 | |
| SCHEMBL10999345 | 0.72 | LMNA (0.39) | CRBNFKBP5LMNAHSD17B10 | |
| SCHEMBL11004614 | 0.72 | LMNA (0.39) | CRBNFKBP5LMNAHSD17B10 | |
| SCHEMBL10668871 | 0.71 | OR51E2 (0.42) | CRBNFKBP5LMNAHSD17B10OR51E2 | |
| SCHEMBL6665501 | 0.70 | CRBN (0.50) | CRBNFKBP5KDM4EGAAPOLB | |
| SCHEMBL11005699 | 0.69 | HSD17B10 (0.56) | CRBNFKBP5LMNAHSD17B10KDM4E | |
| SCHEMBL4662855 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4537616-A | Herbicidal 2,6-dioxocyclohexylidene derivatives | UNION CARBIDE CORPORATION (US) | 1985-08-27 | — | — | US | disclosed |