Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11003895 | 0.98 | LMNA (0.49) | HSD17B10LMNAALDH1A1FKBP5CRBN | |
| SCHEMBL11005699 | 0.94 | HSD17B10 (0.56) | HSD17B10LMNAALDH1A1FKBP5CRBN | |
| SCHEMBL11003902 | 0.83 | LMNA (0.45) | HSD17B10LMNAFKBP5CRBN | |
| SCHEMBL10999924 | 0.79 | LMNA (0.40) | HSD17B10LMNAFKBP5CRBN | |
| SCHEMBL10999239 | 0.77 | LMNA (0.50) | HSD17B10LMNAOR51E2 | |
| SCHEMBL11033532 | 0.76 | CRBN (0.44) | HSD17B10LMNAALDH1A1FKBP5CRBN | |
| SCHEMBL10997794 | 0.75 | ALDH1A1 (0.46) | HSD17B10LMNAALDH1A1GAAKDM4E | |
| SCHEMBL4580150 | 0.74 | MEN1 (0.44) | HSD17B10LMNAALDH1A1GAAKDM4E | |
| SCHEMBL10999345 | 0.74 | LMNA (0.39) | HSD17B10LMNAFKBP5CRBN | |
| SCHEMBL11004712 | 0.71 | GAA (0.37) | HSD17B10LMNAALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4537616-A | Herbicidal 2,6-dioxocyclohexylidene derivatives | UNION CARBIDE CORPORATION (US) | 1985-08-27 | — | — | US | disclosed |