Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069881 | 0.87 | LMNA (0.50) | LMNAMAPTPOLBPKMCYP3A4 | |
| SCHEMBL1824696 | 0.81 | ALDH1A1 (0.42) | LMNAMAPTPOLBPKMCYP3A4 | |
| SCHEMBL8994714 | 0.79 | LMNA (0.53) | LMNAMAPTPOLBPKMCYP3A4 | |
| SCHEMBL12175042 | 0.79 | ALDH1A1 (0.70) | MAPTPOLBCYP3A4KDM4ETSHR | |
| SCHEMBL10299137 | 0.79 | ALDH1A1 (0.70) | MAPTPOLBCYP3A4KDM4ETSHR | |
| SCHEMBL12175072 | 0.79 | ALDH1A1 (0.70) | MAPTPOLBCYP3A4KDM4ETSHR | |
| SCHEMBL24747284 | 0.78 | LMNA (0.62) | LMNAMAPTPOLBPKMCYP3A4 | |
| SCHEMBL15700661 | 0.78 | LMNA (0.61) | LMNAMAPTPOLBPKMCYP3A4 | |
| SCHEMBL2359443 | 0.78 | LMNA (0.52) | LMNAMAPTPOLBPKMCYP3A4 | |
| SCHEMBL269329 | 0.77 | LMNA (0.80) | LMNAMAPTPOLBPKMCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59088444-A | — | — | None | — | — | JP | disclosed |
| JP-S5988444-A | NOVEL ACYLOIN COMPOUND, ITS PRODUCTION AND USE | UENO SEIYAKU OYO KENKYUSHO:KK | 1984-05-22 | — | — | JP | disclosed |