Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18573447 | 0.86 | ALDH1A1 (0.75) | ALDH1A1TSHRNPSR1HTTLMNA | |
| SCHEMBL7355629 | 0.80 | ALDH1A1 (0.67) | ALDH1A1HTTLMNACA2CA1 | |
| SCHEMBL4614428 | 0.80 | ALDH1A1 (0.67) | ALDH1A1HTTLMNACA2CA1 | |
| SCHEMBL48345 | 0.77 | ALDH1A1 (0.62) | ALDH1A1TSHRNPSR1PRMT3CARM1 | |
| SCHEMBL21118113 | 0.77 | ALDH1A1 (0.62) | ALDH1A1HTTLMNACA2CA1 | |
| SCHEMBL3151454 | 0.75 | ALDH1A1 (0.60) | ALDH1A1TSHRNPSR1PRMT3CARM1 | |
| SCHEMBL5114807 | 0.75 | ALDH1A1 (0.60) | ALDH1A1HTTLMNACA2CA1 | |
| SCHEMBL8018138 | 0.75 | ALDH1A1 (0.60) | ALDH1A1TSHRNPSR1PRMT3CARM1 | |
| SCHEMBL4614425 | 0.75 | ALDH1A1 (0.60) | ALDH1A1HTTLMNACA2CA1 | |
| SCHEMBL3759352 | 0.75 | ALDH1A1 (0.60) | ALDH1A1HTTLMNACA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0093765-A4 | 2-HYDROXYPROPYLAMINE ARYL ESTER DERIVATIVES. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1984-04-27 | — | — | EP | disclosed |
| EP-0093765-A1 | 2-HYDROXYPROPYLAMINE ARYL ESTER DERIVATIVES. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1983-11-16 | — | — | EP | disclosed |
| WO-1983001770-A1 | 2-HYDROXYPROPYLAMINE ARYL ESTER DERIVATIVES | AMERICAN HOSPITAL SUPPLY CORP (US) | 1983-05-26 | — | — | WO | disclosed |