Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6475097 | 0.79 | CHRM2 (0.58) | POLBCHRM2MEN1CHRM4CHRM5 | |
| SCHEMBL852252 | 0.78 | — | — | |
| SCHEMBL10988563 | 0.74 | MAPT (0.41) | POLBCHRM2MEN1CHRM4CHRM5 | |
| SCHEMBL3723023 | 0.73 | — | — | |
| SCHEMBL11839445 | 0.71 | — | — | |
| SCHEMBL3183110 | 0.71 | — | — | |
| SCHEMBL1362084 | 0.71 | — | — | |
| SCHEMBL3533067 | 0.71 | — | — | |
| SCHEMBL8143743 | 0.70 | POLB (0.52) | POLBCHRM2MEN1CHRM4CHRM5 | |
| SCHEMBL903315 | 0.69 | CHRM2 (0.58) | POLBCHRM2MEN1CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59038392-A | — | — | None | — | — | JP | disclosed |
| JP-S5938392-A | MANUFACTURE OF 2-PROPARGYL-3-METHYL-4-HYDROXY-2- CYCLOPENTENONE | SUMITOMO CHEM CO LTD | 1984-03-02 | — | — | JP | disclosed |