Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11031566 | 0.99 | MME (0.50) | MMEMMP3ECE1LTA4H | |
| SCHEMBL11031934 | 0.96 | MME (0.53) | MMEMMP3ECE1LTA4H | |
| Monoethanolamine SCHEMBL11032722 | 0.89 | MME (0.54) | MMEECE1LTA4H | |
| SCHEMBL11032754 | 0.87 | MME (0.54) | MMEECE1 | |
| SCHEMBL11032948 | 0.87 | MME (0.54) | MMEECE1 | |
| SCHEMBL11033973 | 0.86 | MME (0.55) | MMEECE1 | |
| SCHEMBL11034213 | 0.86 | MMP3 (0.47) | MMEMMP3ECE1 | |
| SCHEMBL11031714 | 0.85 | MME (0.56) | MMEECE1 | |
| SCHEMBL11031571 | 0.85 | MMP3 (0.48) | MMEMMP3ECE1 | |
| SCHEMBL11033335 | 0.83 | MME (0.58) | MMEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432972-A | HYPOTENSIVE AGENTS, KANALGESICS, AND ANGIOTENSIN AND ENKEPHALIN INHIBITION | E. R. SQUIBB & SONS, INC. (US) | 1984-02-21 | — | — | US | disclosed |