SCHEMBL11034243

SCHEMBL11034243

Cc1ccc([As](=O)(O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
KDM4E B2RXH2 1/20 0.56
RAB9A P51151 1/20 0.56
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55
ALDH1A1 P00352 7/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
TP53 P04637 2/20 0.54
CYP2C19 P33261 2/20 0.54
HPGD P15428 2/20 0.54
CYP2C9 P11712 1/20 0.54
ALOX15 P16050 1/20 0.54
HSD17B10 Q99714 1/20 0.54
TASP1 Q9H6P5 1/20 0.54
KMT2A Q03164 3/20 0.50
MAPT P10636 2/20 0.46
LMNA P02545 4/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22999953 0.85 KDM4E (0.72) TSHRKDM4ERAB9ACA4CA6
SCHEMBL9112179 0.79 ACHE (0.53) TSHRCA6CA7CA9ALDH1A1
SCHEMBL23000006 0.77 KDM4E (0.62) TSHRKDM4ERAB9ACA4CA6
SCHEMBL9177404 0.75 TDP1 (0.65) TSHRRAB9ACA4CA6CA7
SCHEMBL3056859 0.74 MAPT (0.74) TSHRKDM4ERAB9ACA4CA6
SCHEMBL11078484 0.72 TSHR (0.56) TSHRKDM4ERAB9ACA4CA6
SCHEMBL20916723 0.72 KDM4E (0.56) TSHRKDM4ERAB9ACA4CA6
SCHEMBL20916722 0.72 KDM4E (0.56) TSHRKDM4ERAB9ACA4CA6
Arsanilic Acid SCHEMBL160507 0.72 KDM4E (1.00) TSHRKDM4ERAB9ACA4CA6
Arsanilic Acid SCHEMBL4837583 0.72 KDM4E (1.00) TSHRKDM4ERAB9ACA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0070155-B1 PROCESS OF PREPARING A KETAZINE FROM A KETONE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1984-10-10 EP claimed
US-4473708-A REACTING KETONE WITH AMMONIA AND HYDROGEN PEROXIDE MITSUBISHI GAS CHEMICAL COMPANY INC. (JP) 1984-09-25 US claimed
US-4410715-A Process for the epoxidation of olefins using a group V metal co-catalyst I and a phenolic hydrocarbon co-catalyst II EXXON RESEARCH & ENGINEERING CO. (US) 1983-10-18 US claimed
EP-0070155-A1 Process of preparing a ketazine from a ketone MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1983-01-19 EP claimed
EP-0070155-B1 PROCESS OF PREPARING A KETAZINE FROM A KETONE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1984-10-10 EP disclosed
US-4473708-A REACTING KETONE WITH AMMONIA AND HYDROGEN PEROXIDE MITSUBISHI GAS CHEMICAL COMPANY INC. (JP) 1984-09-25 US disclosed
US-4410715-A Process for the epoxidation of olefins using a group V metal co-catalyst I and a phenolic hydrocarbon co-catalyst II EXXON RESEARCH & ENGINEERING CO. (US) 1983-10-18 US disclosed
EP-0070155-A1 Process of preparing a ketazine from a ketone MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1983-01-19 EP disclosed