Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542888 | 0.77 | CYP2A6 (0.56) | CYP2A6CA12CA1CA9CA2 | |
| SCHEMBL8252613 | 0.75 | CYP2A6 (0.55) | CYP2A6CA12CA1CA9CA2 | |
| SCHEMBL11035090 | 0.75 | CYP2A6 (0.55) | CYP2A6CA12CA1CA9CA2 | |
| SCHEMBL546445 | 0.75 | CYP2A6 (0.59) | CYP2A6CA12CA1CA9CA2 | |
| SCHEMBL450134 | 0.75 | CA12 (0.60) | CYP2A6CA12CA1CA9CA2 | |
| SCHEMBL2670683 | 0.75 | NQO1 (0.62) | CYP2A6CA12CA1CA9CA2 | |
| SCHEMBL15842364 | 0.75 | CYP2A6 (0.55) | CYP2A6CA12CA1CA9CA2 | |
| SCHEMBL1535058 | 0.75 | NQO1 (0.62) | CA12CA1CA9LMNACYP3A4 | |
| SCHEMBL15842643 | 0.72 | CYP2A6 (0.51) | CYP2A6CA12CA1CA9CA2 | |
| SCHEMBL6560665 | 0.72 | CYP2A6 (0.60) | CYP2A6CA12CA1CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024182788-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |
| US-4441969-A | ARYL HYDROXY CARBOXYLIC ACID | OMI INTERNATIONAL CORPORATION (US) | 1984-04-10 | — | — | US | disclosed |