Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.60 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18483310 | 0.82 | CYP2A6 (0.50) | CYP2A6HSD17B3CYP3A4KCNA3CA12 | |
| SCHEMBL8372531 | 0.77 | HSD17B3 (0.62) | HSD17B3CYP3A4CA12CA1LMNA | |
| SCHEMBL10520417 | 0.76 | CYP2A6 (0.44) | CYP2A6HSD17B3CYP3A4KCNA3CA12 | |
| SCHEMBL546445 | 0.76 | CYP2A6 (0.59) | CYP2A6HSD17B3CYP3A4KCNA3CA12 | |
| SCHEMBL8750124 | 0.76 | CTRC (0.48) | CYP2A6HSD17B3CYP3A4CTRCCA12 | |
| SCHEMBL11036109 | 0.75 | CYP2A6 (1.00) | CYP2A6CYP3A4KCNA3CA12CA1 | |
| SCHEMBL15842599 | 0.75 | CYP2A6 (0.54) | CYP2A6HSD17B3CYP3A4KCNA3CA12 | |
| SCHEMBL8750145 | 0.74 | HSD17B3 (0.58) | HSD17B3LMNAMCL1TDP1ALOX15 | |
| SCHEMBL15842600 | 0.74 | HSD17B3 (0.58) | HSD17B3CTRCKCNA3LMNATSHR | |
| SCHEMBL5542888 | 0.74 | CYP2A6 (0.56) | CYP2A6CYP3A4KCNA3CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9127092-B2 | Method for producing polydienes and polydiene copolymers with reduced cold flow | BRIDGESTONE CORPORATION (JP) | 2015-09-08 | — | — | US | claimed |
| US-20140187725-A1 | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2014-07-03 | — | — | US | claimed |
| US-5639893-A | Process for producing octahydrocoumarins and same as a product of such process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-17 | — | — | US | claimed |
| EP-0757989-A1 | A process for producing octahydrocoumarins and same as a product of such process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-12 | — | — | EP | claimed |
| US-20230119408-A1 | NUCLEOTIDE ANALOGS AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-04-20 | — | — | US | disclosed |
| US-20230002436-A1 | MODIFIED NUCLEOTIDES AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-01-05 | — | — | US | disclosed |
| US-11174281-B1 | Modified nucleotides and uses thereof | Singular Genomics Systems, Inc. (US) | 2021-11-16 | — | — | US | disclosed |
| US-9127092-B2 | Method for producing polydienes and polydiene copolymers with reduced cold flow | BRIDGESTONE CORPORATION (JP) | 2015-09-08 | — | — | US | disclosed |
| US-20140187725-A1 | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2014-07-03 | — | — | US | disclosed |
| EP-0994176-B1 | Single phase liquid mixture of benzophenone and mixture of at least two other normally solid perfumery substances and perfumery uses thereof | INT FLAVORS & FRAGRANCES INC (US) | 2004-01-28 | — | — | EP | disclosed |
| EP-0994176-A2 | Single phase liquid mixture of benzophenone and mixture of at least two other normally solid perfumery substances and perfumery uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2000-04-19 | — | — | EP | disclosed |
| US-5639893-A | Process for producing octahydrocoumarins and same as a product of such process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0757989-A1 | A process for producing octahydrocoumarins and same as a product of such process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230119408-A1 | NUCLEOTIDE ANALOGS AND USES THEREOF | NUDT1, PNP, NT5C2 | CYP2A6 1878/4885HSD17B3 4367/4885CYP3A4 1953/4885 |
| US-20230002436-A1 | MODIFIED NUCLEOTIDES AND USES THEREOF | NUDT1, RNMT, ADAR | CYP2A6 2068/4885HSD17B3 4788/4885CYP3A4 2585/4885 |
| US-11174281-B1 | Modified nucleotides and uses thereof | NUDT1, RNMT, ADAR | CYP2A6 2068/4885HSD17B3 4788/4885CYP3A4 2585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.