Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 17/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340362 | 0.83 | CYP2C19 (0.39) | CYP3A4CYP2D6CYP2C9CYP2C19ADH1B | |
| SCHEMBL1834441 | 0.78 | TAAR1 (0.48) | CYP3A4CYP2C19ADH1BADH1CADH1A | |
| SCHEMBL824894 | 0.78 | ALDH1A1 (0.41) | KIF11CYP2C19ADH1BADH1CADH1A | |
| SCHEMBL6367386 | 0.77 | KIF11 (0.48) | KIF11CYP11B1CYP11B2KCNH2CYP3A4 | |
| SCHEMBL1974668 | 0.77 | KIF11 (0.48) | KIF11CYP11B1CYP11B2KCNH2CYP3A4 | |
| SCHEMBL28954005 | 0.77 | KIF11 (0.48) | KIF11CYP11B1CYP11B2KCNH2CYP3A4 | |
| SCHEMBL1149158 | 0.77 | KIF11 (0.64) | KIF11CYP11B1CYP11B2KCNH2CYP3A4 | |
| SCHEMBL440368 | 0.76 | KIF11 (0.41) | KIF11CYP11B1CYP11B2CYP2C19 | |
| SCHEMBL27360229 | 0.74 | KCNN4 (0.40) | KIF11KCNH2CYP2C19ADH1BADH1C | |
| SCHEMBL27753815 | 0.73 | KIF11 (0.54) | KIF11CYP11B1CYP11B2KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59198448-A | — | — | None | — | — | JP | disclosed |
| JP-59196311-A | — | — | None | — | — | JP | disclosed |
| JP-S59198448-A | RADIATION-SENSITIVE ORGANIC HIGH POLYMER MATERIAL | HITACHI LTD | 1984-11-10 | — | — | JP | disclosed |
| JP-S59196311-A | ALDEHYDE COPOLYMER | DAICEL CHEM IND LTD | 1984-11-07 | — | — | JP | disclosed |